ELK1

GENERAL INFORMATION

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Gene name

ELK1

Gene description

ELK1, member of ETS oncogene family

Protein class

Predicted intracellular proteins
RAS pathway related proteins
Transcription factors

Predicted localization

Intracellular

Number of transcripts

5
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HUMAN PROTEIN ATLAS INFORMATION

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RNA tissue category

HPA:Expressed in all
GTEx:Expressed in all

Protein evidence

Evidence at protein level

Protein localization

Nuclear expression, most abundant in glandular cells.

ANTIBODY RELIABILITY

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Data reliability
description

Antibody staining mainly consistent with RNA expression data. Pending external verification.

Data reliability

Supportive based on 2 antibodies.
HPA036084 , CAB003808
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RNA AND PROTEIN EXPRESSION SUMMARY

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RNA expression (FPKM) Protein expression (score)
Brain
Endocrine tissues
Bone marrow & immune system
Muscle tissues
Lung
Liver & gallbladder
Pancreas
Gastrointestinal tract
Kidney & urinary bladder
Male tissues
Female tissues
Adipose & soft tissue
Skin
Cerebral cortex

Lymph node

Liver

Colon

Kidney

Testis

Ovary



PROTEIN EXPRESSION OVERVIEW

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Organ

Expression



RNA EXPRESSION OVERVIEW

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HPA dataset
RNA tissue category:  Expressed in all

Organ

Expression

GTEx dataset
RNA tissue category:  Expressed in all

Organ

Expression



GENE INFORMATION

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Gene name

ELK1

Synonyms

Description

ELK1, member of ETS oncogene family (HGNC Symbol)

Entrez gene summary

This gene is a member of the Ets family of transcription factors and of the ternary complex factor (TCF) subfamily. Proteins of the TCF subfamily form a ternary complex by binding to the the serum response factor and the serum response element in the promoter of the c-fos proto-oncogene. The protein encoded by this gene is a nuclear target for the ras-raf-MAPK signaling cascade. This gene produces multiple isoforms by using alternative translational start codons and by alternative splicing. Related pseudogenes have been identified on chromosomes 7 and 14. [provided by RefSeq, Mar 2012]

Chromosome

X

Cytoband

p11.23

Chromosome location (bp)

47635521 - 47650604

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000126767 (version 78.38)

Entrez gene

2002

UniProt

P19419 (UniProt - Evidence at protein level)

neXtProt

NX_P19419

Antibodypedia

ELK1 antibodies


PROTEIN BROWSER

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ENST00000247161
 
ENST00000343894
 
ENST00000376983
 
ENST00000592066
 
ENST00000619324
 
 
 
 


PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

ELK1-001 ENSP00000247161
ENST00000247161
P19419
Show all »
Show » Show » 428 44.9 No 0
ELK1-002 ENSP00000366182
ENST00000376983
P19419
Show all »
Show » Show » 428 44.9 No 0
ELK1-005 ENSP00000467055
ENST00000592066
K7ENR1
Show all »
Show » Show » 374 38.7 No 0
ELK1-201 ENSP00000345585
ENST00000343894
P19419
Show all »
Show » Show » 95 11.2 No 0
ELK1-202 ENSP00000483056
ENST00000619324
P19419
Show all »
Show » Show » 428 44.9 No 0