AKAP9

GENERAL INFORMATION

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Gene name

AKAP9

Gene description

A kinase (PRKA) anchor protein 9

Protein class

Cancer-related genes
Cytoskeleton related proteins
Disease related genes
Plasma proteins
Predicted intracellular proteins
Predicted membrane proteins

Predicted localization

Intracellular,Membrane

Number of transcripts

8
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HUMAN PROTEIN ATLAS INFORMATION

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RNA tissue category

HPA:Expressed in all
GTEx:Expressed in all

Protein evidence

Evidence at protein level

Protein localization

Ubiquitous cytoplasmic staining.

ANTIBODY RELIABILITY

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Data reliability
description

Antibody staining mainly consistent with RNA expression data.

Data reliability

Supportive based on 3 antibodies.
HPA008548 , HPA026109 , CAB012909
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RNA AND PROTEIN EXPRESSION SUMMARY

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RNA expression (FPKM) Protein expression (score)
Brain
Endocrine tissues
Bone marrow & immune system
Muscle tissues
Lung
Liver & gallbladder
Pancreas
Gastrointestinal tract
Kidney & urinary bladder
Male tissues
Female tissues
Adipose & soft tissue
Skin
Cerebral cortex

Lymph node

Liver

Gallbladder

Colon

Kidney

Testis



PROTEIN EXPRESSION OVERVIEW

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Organ

Expression



RNA EXPRESSION OVERVIEW

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HPA dataset
RNA tissue category:  Expressed in all

Organ

Expression

GTEx dataset
RNA tissue category:  Expressed in all

Organ

Expression



GENE INFORMATION

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Gene name

AKAP9 (HGNC Symbol)

Synonyms

AKAP350, AKAP450, CG-NAP, HYPERION, KIAA0803, LQT11, MU-RMS-40.16A, PPP1R45, PRKA9, YOTIAO

Description

A kinase (PRKA) anchor protein 9 (HGNC Symbol)

Entrez gene summary

The A-kinase anchor proteins (AKAPs) are a group of structurally diverse proteins which have the common function of binding to the regulatory subunit of protein kinase A (PKA) and confining the holoenzyme to discrete locations within the cell. This gene encodes a member of the AKAP family. Alternate splicing of this gene results in at least two isoforms that localize to the centrosome and the Golgi apparatus, and interact with numerous signaling proteins from multiple signal transduction pathways. These signaling proteins include type II protein kinase A, serine/threonine kinase protein kinase N, protein phosphatase 1, protein phosphatase 2a, protein kinase C-epsilon and phosphodiesterase 4D3. [provided by RefSeq, Aug 2008]

Chromosome

7

Cytoband

q21.2

Chromosome location (bp)

91940867 - 92110673

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000127914 (version 78.38)

Entrez gene

10142

UniProt

Q99996 (UniProt - Evidence at protein level)

neXtProt

NX_Q99996

Antibodypedia

AKAP9 antibodies


PROTEIN BROWSER

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ENST00000356239
 
ENST00000358100
 
ENST00000359028
 
ENST00000394534
 
ENST00000394564
 
ENST00000435423
 
ENST00000438114
 
ENST00000619023
 
 
 
 


PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

AKAP9-001 ENSP00000348573
ENST00000356239
Q99996
Show all »
Show » Show » 3907 453 No 0
AKAP9-002 ENSP00000378065
ENST00000394564
Q6PJH3
Show all »
Show » Show » 314 36.2 No 0
AKAP9-005 ENSP00000406937
ENST00000435423
Show » 318 36.1 No 1
AKAP9-006 ENSP00000378042
ENST00000394534
H7BYL6
Show all »
Show » Show » 1769 204 No 0
AKAP9-011 ENSP00000391704
ENST00000438114
H7BZV6
Show all »
Show » Show » 232 26.5 No 0
AKAP9-201 ENSP00000350813
ENST00000358100
Show » 3126 362.6 No 1
AKAP9-202 ENSP00000351922
ENST00000359028
Q8IW64
Show all »
Show » 3910 453.5 No 0
AKAP9-203 ENSP00000480807
ENST00000619023
Show » 1637 190.7 No 0