The primary data page shows the detailed antibody staining in 76 different cell types for each analyzed antibody. In addition, for each cell type, a knowledge-based annotated protein expression score based on all analyzed antibodies is displayed furthest to the right. The images and annotations can be accessed by clicking on the tissue name or score bar. More information can be found in Assays & Annotation.
The tissues and cell types can be ordered by organ, cell type or alphabetically. If ordered by organ, the tissues are presented in groups according to functional features. If ordered by cell type, the cells are presented in groups related to origin.
This score describes the level of antibody staining observed in the annotated cell types as not detected (n), low (l), medium (m) or high (h). It is based on the staining intensity and fraction of stained cells. The images and annotations can be accessed by clicking on the tissue name or score bar. More information can be found in Assays & Annotation.
This score describes a knowledge-based best estimate of the protein expression in the annotated cell types as not detected (n), low (l), medium (m) or high (h). It is a result of stringent evaluation of immunohistochemical staining pattern, RNA data from internal and external sources and available protein/gene characterization data. More information can be found in Assays & Annotation.
Summarizing texts describe the staining pattern for each antibody based on staining intensity, fraction of stained cells and subcellular localization. More information can be found in Assays & Annotation.
Distinct cytoplasmic and membranous staining of all epithelial cells except hepatocytes. Testis, lymphoid tissues, ovaries and CNS were negative.
Strong and distinct cytoplasmic and membranous staining in glandular cells of the gastrointestinal tract, urinary bladder and squamous epithelium was displayed. Distinct positivity of basal cells in the prostate epithelium and seminal vesicles was observed. Remaining normal cells were generally negative.
Strong cytoplasmic staining was observed in myoepithelial cells in breast, basal layers in respiratory epithelia, epididymis, fallopian tube, oral mucosa, prostate, salivary gland, seminal vesicle and vulva. Urinary bladder displayed additional membranous positivity. Leydig cells were moderately stained. Remaining normal tissues were generally negative.
Moderate to strong cytoplasmic and membranous immunoreactivity was observed in basal cells of urothelium, respiratory epithelium, squamous epithelium of tonsil, esophagus and oral mucosa, and in prostate, epididymis, breast, cervix, salivary glands and hair follicles in skin. Weak to moderate granular positivity was seen in a subset of neurons within the CNS. Remaining normal tissues were weak or negative.