COPB1

GENERAL INFORMATION

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Gene name

COPB1

Gene description

Coatomer protein complex, subunit beta 1

Protein class

Plasma proteins
Predicted intracellular proteins

Predicted localization

Intracellular

Number of transcripts

5
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HUMAN PROTEIN ATLAS INFORMATION

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RNA tissue category

HPA:Expressed in all
GTEx:Expressed in all

Protein evidence

Evidence at protein level

Protein localization

Ubiquitous cytoplasmic expression often with a granular pattern.

ANTIBODY RELIABILITY

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Data reliability
description

Pending RNA-based expert annotation.

Data reliability

Supportive based on 3 antibodies.
HPA043954 , HPA064403 , CAB012338
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RNA AND PROTEIN EXPRESSION SUMMARY

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RNA expression (FPKM) Protein expression (score)
Brain
Endocrine tissues
Bone marrow & immune system
Muscle tissues
Lung
Liver & gallbladder
Pancreas
Gastrointestinal tract
Kidney & urinary bladder
Male tissues
Female tissues
Adipose & soft tissue
Skin
Cerebral cortex

Lymph node

Liver

Colon

Kidney

Urinary bladder

Testis



PROTEIN EXPRESSION OVERVIEW

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Organ

Expression



RNA EXPRESSION OVERVIEW

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HPA dataset
RNA tissue category:  Expressed in all

Organ

Expression

GTEx dataset
RNA tissue category:  Expressed in all

Organ

Expression



GENE INFORMATION

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Gene name

COPB1 (HGNC Symbol)

Synonyms

COPB

Description

Coatomer protein complex, subunit beta 1 (HGNC Symbol)

Entrez gene summary

This gene encodes a protein subunit of the coatomer complex associated with non-clathrin coated vesicles. The coatomer complex, also known as the coat protein complex 1, forms in the cytoplasm and is recruited to the Golgi by activated guanosine triphosphatases. Once at the Golgi membrane, the coatomer complex may assist in the movement of protein and lipid components back to the endoplasmic reticulum. Alternatively spliced transcript variants have been described. [provided by RefSeq, Jan 2009]

Chromosome

11

Cytoband

p15.2

Chromosome location (bp)

14443440 - 14500027

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000129083 (version 78.38)

Entrez gene

1315

UniProt

P53618 (UniProt - Evidence at protein level)

neXtProt

NX_P53618

Antibodypedia

COPB1 antibodies


PROTEIN BROWSER

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ENST00000249923
 
ENST00000439561
 
ENST00000529866
 
ENST00000534234
 
ENST00000534771
 
 
 
 


PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

COPB1-001 ENSP00000249923
ENST00000249923
P53618
Show all »
Show » Show » 953 107.1 No 0
COPB1-002 ENSP00000397873
ENST00000439561
P53618
Show all »
Show » Show » 953 107.1 No 0
COPB1-003 ENSP00000436383
ENST00000534234
E9PP73
Show all »
Show » Show » 486 55.5 No 0
COPB1-004 ENSP00000436401
ENST00000534771
E9PP63
Show all »
Show » Show » 132 15.1 No 0
COPB1-012 ENSP00000431530
ENST00000529866
E9PKQ1
Show all »
Show » Show » 137 15.7 No 0