ATP8B3

GENERAL INFORMATION

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Gene name

ATP8B3

Gene description

ATPase, aminophospholipid transporter, class I, type 8B, member 3

Protein class

Enzymes
Predicted membrane proteins

Predicted localization

Membrane

Number of transcripts

5
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HUMAN PROTEIN ATLAS INFORMATION

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RNA tissue category

HPA:Tissue enriched (testis)
GTEx:Tissue enriched (testis)

Protein evidence

Evidence at protein level

Protein localization

RNA data suggests expression in testis. RNA-based expert annotation gave inconclusive results.

ANTIBODY RELIABILITY

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Data reliability
description

Antibody staining not consistent with RNA expression data. Pending external verification. Presumed off target binding observed and disregarded.

Data reliability

Uncertain based on 2 antibodies.
HPA041992 , HPA043582
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RNA AND PROTEIN EXPRESSION SUMMARY

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RNA expression (FPKM) Protein expression (score)
Brain
N/A
Endocrine tissues
N/A
Bone marrow & immune system
N/A
Muscle tissues
N/A
Lung
N/A
Nasopharynx
N/A
N/A
Bronchus
N/A
N/A
Lung
N/A
Liver & gallbladder
N/A
Liver
N/A
Pancreas
N/A
Pancreas
N/A
Gastrointestinal tract
N/A
Kidney & urinary bladder
N/A
Male tissues
N/A
Testis
N/A
Epididymis
N/A
N/A
Prostate
N/A
Seminal vesicle
N/A
N/A
Female tissues
N/A
Breast
N/A
N/A
Vagina
N/A
N/A
Cervix, uterine
N/A
N/A
Ovary
N/A
Placenta
N/A
Adipose & soft tissue
N/A
Skin
N/A
Skin
N/A
Cerebral cortex

Lymph node

Liver

Colon

Kidney

Testis



PROTEIN EXPRESSION OVERVIEW

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RNA-based expert annotation could not be performed, due to inconclusive results. View immunohistochemistry primary data.


RNA EXPRESSION OVERVIEW

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HPA dataset
RNA tissue category:  Tissue enriched (testis)

Organ

Expression

GTEx dataset
RNA tissue category:  Tissue enriched (testis)

Organ

Expression



GENE INFORMATION

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Gene name

ATP8B3 (HGNC Symbol)

Synonyms

ATPIK

Description

ATPase, aminophospholipid transporter, class I, type 8B, member 3 (HGNC Symbol)

Entrez gene summary

The protein encoded by this gene belongs to the family of P-type cation transport ATPases, and to the subfamily of aminophospholipid-transporting ATPases. The aminophospholipid translocases transport phosphatidylserine and phosphatidylethanolamine from one side of a bilayer to the other. This gene encodes member 3 of phospholipid-transporting ATPase 8B; other members of this protein family are located on chromosomes 1, 15 and 18. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2012]

Chromosome

19

Cytoband

p13.3

Chromosome location (bp)

1782075 - 1812276

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000130270 (version 78.38)

Entrez gene

148229

UniProt

O60423 (UniProt - Evidence at transcript level)

neXtProt

NX_O60423

Antibodypedia

ATP8B3 antibodies


PROTEIN BROWSER

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ENST00000310127
 
ENST00000525591
 
ENST00000526092
 
ENST00000533993
 
ENST00000587160
 
 
 
 


PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

ATP8B3-001 ENSP00000445204
ENST00000526092
F5H3R9
Show all »
Show » Show » 562 64 No 4
ATP8B3-002 ENSP00000311336
ENST00000310127
O60423
Show all »
Show » Show » 1300 146.8 No >9
ATP8B3-004 ENSP00000445883
ENST00000533993
Show » Show » 294 33.3 No 2
ATP8B3-005 ENSP00000437115
ENST00000525591
O60423
Show all »
Show » Show » 1263 143.7 No >9
ATP8B3-009 ENSP00000465027
ENST00000587160
K7EJ52
Show all »
Show » Show » 205 22.9 No 2