ACSS2

GENERAL INFORMATION

? »

Gene name

ACSS2

Gene description

Acyl-CoA synthetase short-chain family member 2

Protein class

Enzymes
Predicted intracellular proteins
Predicted membrane proteins

Predicted localization

Intracellular,Membrane

Number of transcripts

6
SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION

? »

RNA tissue category

HPA:Expressed in all
GTEx:Expressed in all

Protein evidence

Evidence at protein level

Protein localization

Glandular cells in gastrointestinal tract, fallopian tube, placenta, seminal epididymis, hematopoietic cells showed moderate cytoplasmic positivity. Nuclear positivity was observed in testis, skeletal and heart muscle. Lymphatic cells and cells in CNS were mainly negative.

ANTIBODY RELIABILITY

? »

Data reliability
description

Pending RNA-based expert annotation.

Data reliability

Uncertain based on 1 antibody.
HPA004141
SHOW MORE

RNA AND PROTEIN EXPRESSION SUMMARY

? »
RNA expression (FPKM) Protein expression (score)
Brain
Endocrine tissues
Bone marrow & immune system
Muscle tissues
Lung
Nasopharynx
N/A
N/A
Bronchus
N/A
Liver & gallbladder
Pancreas
Gastrointestinal tract
Kidney & urinary bladder
Male tissues
Female tissues
Adipose & soft tissue
Skin
Cerebral cortex

Lymph node

Liver

Duodenum

Colon

Kidney

Testis



PROTEIN EXPRESSION OVERVIEW

? »

Organ

Expression



RNA EXPRESSION OVERVIEW

? »
HPA dataset
RNA tissue category:  Expressed in all

Organ

Expression

GTEx dataset
RNA tissue category:  Expressed in all

Organ

Expression



GENE INFORMATION

? »

Gene name

ACSS2 (HGNC Symbol)

Synonyms

ACAS2, AceCS, ACS, ACSA, dJ1161H23.1

Description

Acyl-CoA synthetase short-chain family member 2 (HGNC Symbol)

Entrez gene summary

This gene encodes a cytosolic enzyme that catalyzes the activation of acetate for use in lipid synthesis and energy generation. The protein acts as a monomer and produces acetyl-CoA from acetate in a reaction that requires ATP. Expression of this gene is regulated by sterol regulatory element-binding proteins, transcription factors that activate genes required for the synthesis of cholesterol and unsaturated fatty acids. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2009]

Chromosome

20

Cytoband

q11.22

Chromosome location (bp)

34872146 - 34927962

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000131069 (version 78.38)

Entrez gene

55902

UniProt

Q9NR19 (UniProt - Evidence at protein level)

neXtProt

NX_Q9NR19

Antibodypedia

ACSS2 antibodies


PROTEIN BROWSER

? »
 
 
 
ENST00000253382
 
ENST00000360596
 
ENST00000473172
 
ENST00000484354
 
ENST00000488172
 
ENST00000493805
 
 
 
 


PROTEIN INFORMATION

? »

Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

ACSS2-001 ENSP00000353804
ENST00000360596
Q9NR19
Show all »
Show » Show » 701 78.6 No 1
ACSS2-006 ENSP00000253382
ENST00000253382
Q9NR19
Show all »
Show » Show » 714 80.1 No 1
ACSS2-012 ENSP00000417783
ENST00000488172
C9J7L5
Show all »
Show » Show » 163 18.7 No 1
ACSS2-016 ENSP00000419167
ENST00000484354
C9JXD9
Show all »
Show » 148 17 No 0
ACSS2-019 ENSP00000418812
ENST00000493805
C9IYL0
Show all »
Show » Show » 182 20.8 No 0
ACSS2-020 ENSP00000419925
ENST00000473172
C9JY31
Show all »
Show » Show » 203 23.1 No 1