CA6

GENERAL INFORMATION

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Gene name

CA6

Gene description

Carbonic anhydrase VI

Protein class

Enzymes
Predicted secreted proteins

Predicted localization

Secreted

Number of transcripts

5
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HUMAN PROTEIN ATLAS INFORMATION

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RNA tissue category

HPA:Tissue enriched (salivary gland)
GTEx:Group enriched (skin)

Protein evidence

Evidence at protein level

Protein localization

Highly specific cytoplasmic expression in salivary gland.

ANTIBODY RELIABILITY

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Data reliability
description

Antibody staining consistent with RNA expression data.

Data reliability

Supportive based on 2 antibodies.
HPA028550 , HPA028692
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RNA AND PROTEIN EXPRESSION SUMMARY

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RNA expression (FPKM) Protein expression (score)
Brain
Endocrine tissues
Bone marrow & immune system
Muscle tissues
Lung
Liver & gallbladder
Pancreas
Gastrointestinal tract
Kidney & urinary bladder
Male tissues
Female tissues
Adipose & soft tissue
Skin
Cerebral cortex

Lymph node

Liver

Salivary gland

Colon

Kidney

Testis



PROTEIN EXPRESSION OVERVIEW

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Organ

Expression



RNA EXPRESSION OVERVIEW

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HPA dataset
RNA tissue category:  Tissue enriched (salivary gland)

Organ

Expression

GTEx dataset
RNA tissue category:  Group enriched (skin)

Organ

Expression



GENE INFORMATION

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Gene name

CA6

Synonyms

Description

Carbonic anhydrase VI (HGNC Symbol)

Entrez gene summary

The protein encoded by this gene is one of several isozymes of carbonic anhydrase. This protein is found only in salivary glands and saliva and protein may play a role in the reversible hydratation of carbon dioxide though its function in saliva is unknown. [provided by RefSeq, Jul 2008]

Chromosome

1

Cytoband

p36.23

Chromosome location (bp)

8945867 - 8975092

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000131686 (version 78.38)

Entrez gene

765

UniProt

P23280 (UniProt - Evidence at protein level)

neXtProt

NX_P23280

Antibodypedia

CA6 antibodies


PROTEIN BROWSER

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ENST00000377436
 
ENST00000377442
 
ENST00000377443
 
ENST00000480186
 
ENST00000549778
 
 
 
 


PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

CA6-001 ENSP00000366662
ENST00000377443
P23280
Show all »
Show » Show » 308 35.4 Yes 0
CA6-002 ENSP00000435280
ENST00000480186
Q8N4G4
Show all »
Show » Show » 179 19.7 Yes 0
CA6-005 ENSP00000366654
ENST00000377436
P23280
Show all »
Show » Show » 313 35.4 Yes 0
CA6-006 ENSP00000366661
ENST00000377442
P23280
Show all »
Show » Show » 248 28.7 Yes 0
CA6-007 ENSP00000447108
ENST00000549778
F8W148
Show all »
Show » Show » 187 21.1 Yes 0