ACTR3B

GENERAL INFORMATION

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Gene name

ACTR3B

Gene description

ARP3 actin-related protein 3 homolog B (yeast)

Protein class

Cytoskeleton related proteins
Predicted intracellular proteins

Predicted localization

Intracellular

Number of transcripts

3
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HUMAN PROTEIN ATLAS INFORMATION

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RNA tissue category

HPA:Expressed in all
GTEx:Expressed in all

Protein evidence

Evidence at protein level

Protein localization

Ubiquitous cytoplasmic expression, high in leukocytes.

ANTIBODY RELIABILITY

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Data reliability
description

Pending RNA-based expert annotation. Caution, targets protein from more than one gene.

Data reliability

Uncertain based on 2 antibodies.
HPA047016 , HPA051683
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RNA AND PROTEIN EXPRESSION SUMMARY

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RNA expression (FPKM) Protein expression (score)
Brain
Endocrine tissues
Bone marrow & immune system
Muscle tissues
Lung
Liver & gallbladder
Pancreas
Gastrointestinal tract
Kidney & urinary bladder
Male tissues
Female tissues
Adipose & soft tissue
Skin
Cerebral cortex

Lymph node

Liver

Colon

Kidney

Testis



PROTEIN EXPRESSION OVERVIEW

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Organ

Expression



RNA EXPRESSION OVERVIEW

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HPA dataset
RNA tissue category:  Expressed in all

Organ

Expression

GTEx dataset
RNA tissue category:  Expressed in all

Organ

Expression



GENE INFORMATION

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Gene name

ACTR3B (HGNC Symbol)

Synonyms

ARP11, ARP3beta

Description

ARP3 actin-related protein 3 homolog B (yeast) (HGNC Symbol)

Entrez gene summary

This gene encodes a member of the actin-related proteins (ARP), which form multiprotein complexes and share 35-55% amino acid identity with conventional actin. The protein encoded by this gene may have a regulatory role in the actin cytoskeleton and induce cell-shape change and motility. Pseudogenes of this gene are located on chromosomes 2, 4, 10, 16, 22 and Y. Alternative splicing results in multiple transcript variants and protein isoforms. [provided by RefSeq, Jul 2012]

Chromosome

7

Cytoband

Chromosome location (bp)

152759749 - 152855378

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000133627 (version 78.38)

Entrez gene

57180

UniProt

Q9P1U1 (UniProt - Evidence at transcript level)

neXtProt

NX_Q9P1U1

Antibodypedia

ACTR3B antibodies


PROTEIN BROWSER

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ENST00000256001
 
ENST00000377776
 
ENST00000397282
 
 
 
 


PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

ACTR3B-001 ENSP00000256001
ENST00000256001
Q9P1U1
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Show » Show » 418 47.6 No 0
ACTR3B-002 ENSP00000380452
ENST00000397282
Q9P1U1
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Show » Show » 330 37.9 No 0
ACTR3B-003 ENSP00000367007
ENST00000377776
Q9P1U1
Show all »
Show » Show » 348 39.7 No 0