DPF2

GENERAL INFORMATION

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Gene name

DPF2

Gene description

D4, zinc and double PHD fingers family 2

Protein class

Plasma proteins
Predicted intracellular proteins

Predicted localization

Intracellular

Number of transcripts

4
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HUMAN PROTEIN ATLAS INFORMATION

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RNA tissue category

HPA:Expressed in all
GTEx:Expressed in all

Protein evidence

Evidence at protein level

Protein localization

Most normal tissues showed moderate to strong cytoplasmic and/or nuclear staining. Liver as well as subsets of cells in CNS and lymphoid tissues were weakly stained or negative.

ANTIBODY RELIABILITY

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Data reliability
description

Pending RNA-based expert annotation.

Data reliability

Uncertain based on 1 antibody.
HPA020880
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RNA AND PROTEIN EXPRESSION SUMMARY

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RNA expression (FPKM) Protein expression (score)
Brain
Endocrine tissues
Bone marrow & immune system
Muscle tissues
Lung
Bronchus
N/A
N/A
Liver & gallbladder
Pancreas
Gastrointestinal tract
Kidney & urinary bladder
Male tissues
Female tissues
Adipose & soft tissue
Skin
Cerebral cortex

Lymph node

Liver

Colon

Kidney

Testis

Skin



PROTEIN EXPRESSION OVERVIEW

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Organ

Expression



RNA EXPRESSION OVERVIEW

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HPA dataset
RNA tissue category:  Expressed in all

Organ

Expression

GTEx dataset
RNA tissue category:  Expressed in all

Organ

Expression



GENE INFORMATION

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Gene name

DPF2 (HGNC Symbol)

Synonyms

BAF45d, REQ, ubi-d4

Description

D4, zinc and double PHD fingers family 2 (HGNC Symbol)

Entrez gene summary

The protein encoded by this gene is a member of the d4 domain family, characterized by a zinc finger-like structural motif. This protein functions as a transcription factor which is necessary for the apoptotic response following deprivation of survival factors. It likely serves a regulatory role in rapid hematopoietic cell growth and turnover. This gene is considered a candidate gene for multiple endocrine neoplasia type I, an inherited cancer syndrome involving multiple parathyroid, enteropancreatic, and pituitary tumors. [provided by RefSeq, Jul 2008]

Chromosome

11

Cytoband

q13.1

Chromosome location (bp)

65333754 - 65353249

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000133884 (version 78.38)

Entrez gene

5977

UniProt

Q92785 (UniProt - Evidence at protein level)

neXtProt

NX_Q92785

Antibodypedia

DPF2 antibodies


PROTEIN BROWSER

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ENST00000252268
 
ENST00000415073
 
ENST00000528416
 
ENST00000531989
 
 
 
 


PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

DPF2-001 ENSP00000436901
ENST00000528416
Q92785
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Show » Show » 391 44.2 No 0
DPF2-002 ENSP00000399714
ENST00000415073
Q92785
Show all »
Show » Show » 207 23.6 No 0
DPF2-003 ENSP00000252268
ENST00000252268
J3KMZ8
Show all »
Show » Show » 405 45.8 No 0
DPF2-010 ENSP00000435887
ENST00000531989
H0YEI1
Show all »
Show » Show » 116 13.4 No 0