Fields »

SUBCELLULAR LOCATION

? »

Main location(s)

Nucleus but not nucleoli, Cytoplasm

Additional location(s)

 

Staining summary

Localized to nucleus and cytoplasm.

Reliability (APE)

Low

Antibodies in assay

HPA018155, CAB026025
 

Antibody HPA018155

 

Antibody CAB026025

 

         Cell line A-431

Toggle channels

 
 

Location(s)

Nucleus but not nucleoli, Cytoplasm  

Staining characteristics

Granular  

Staining intensity

Moderate Negative 

Validation

Not decisive - One/multiple location(s) where experimental gene/protein characterization data is partly supporting and partly conflicting.
 
No staining.
 

Comment

  

         Cell line U-2 OS

Toggle channels

 
 

Location(s)

Cytoplasm  

Staining characteristics

Granular  

Staining intensity

Weak Negative 

Validation

Not decisive - One/multiple location(s) where experimental gene/protein characterization data is partly supporting and partly conflicting.
 
No staining.
 

Comment

  

         Cell line U-251 MG

Toggle channels

   

Location(s)

Nucleus but not nucleoli, Cytoplasm   

Staining characteristics

Granular   

Staining intensity

Moderate   

Validation

Not decisive - One/multiple location(s) where experimental gene/protein characterization data is partly supporting and partly conflicting.
   

Comment

   

         Antibody summary


Immunofluorescent staining of human cell line A-431 shows positivity in nucleus but not nucleoli & cytoplasm.
 

Immunofluorescent staining of human cell line A-431 shows no positivity.
 

Summary

Staining of cytoplasm in all three cell lines with additional staining of nucleus in U-251 MG and A-431.   No staining was observed in any of the three cell lines.  

Validation

The subcellular location is partly supported by literature or no literature is available.
 
The subcellular location is partly supported by literature or no literature is available.
 

Dictionary

Cytoplasm
Nucleus but not nucleoli