ADAMTS7

GENERAL INFORMATION

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Gene name

ADAMTS7

Gene description

ADAM metallopeptidase with thrombospondin type 1 motif, 7

Protein class

Enzymes
Plasma proteins
Predicted secreted proteins

Predicted localization

Secreted

Number of transcripts

1
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HUMAN PROTEIN ATLAS INFORMATION

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RNA tissue category

HPA:Mixed
GTEx:Tissue enhanced (heart muscle)

Protein evidence

Evidence at protein level

Protein localization

Nuclear and cytoplasmic expression in most tissues.

ANTIBODY RELIABILITY

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Data reliability
description

Antibody staining mainly consistent with RNA expression data.

Data reliability

Uncertain based on 2 antibodies.
HPA034581 , HPA045284
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RNA AND PROTEIN EXPRESSION SUMMARY

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RNA expression (FPKM) Protein expression (score)
Brain
Endocrine tissues
Bone marrow & immune system
Muscle tissues
Lung
Liver & gallbladder
Pancreas
Gastrointestinal tract
Kidney & urinary bladder
Male tissues
Female tissues
Adipose & soft tissue
Skin
Cerebral cortex

Lymph node

Heart muscle

Liver

Colon

Kidney

Testis



PROTEIN EXPRESSION OVERVIEW

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Organ

Expression



RNA EXPRESSION OVERVIEW

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HPA dataset
RNA tissue category:  Mixed

Organ

Expression

GTEx dataset
RNA tissue category:  Tissue enhanced (heart muscle)

Organ

Expression



GENE INFORMATION

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Gene name

ADAMTS7 (HGNC Symbol)

Synonyms

ADAM-TS7, DKFZp434H204

Description

ADAM metallopeptidase with thrombospondin type 1 motif, 7 (HGNC Symbol)

Entrez gene summary

The protein encoded by this gene is a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) family. Members of this family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The protein encoded by this gene contains two C-terminal TS motifs. [provided by RefSeq, Jul 2008]

Chromosome

15

Cytoband

q25.1

Chromosome location (bp)

78759203 - 78811431

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000136378 (version 78.38)

Entrez gene

11173

UniProt

Q9UKP4 (UniProt - Evidence at protein level)

neXtProt

NX_Q9UKP4

Antibodypedia

ADAMTS7 antibodies


PROTEIN BROWSER

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ENST00000388820
 
 
 
 


PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

ADAMTS7-001 ENSP00000373472
ENST00000388820
Q9UKP4
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