ATP6V1G1

GENERAL INFORMATION

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Gene name

ATP6V1G1

Gene description

ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G1

Protein class

Plasma proteins
Predicted intracellular proteins
Transporters

Predicted localization

Intracellular

Number of transcripts

1
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HUMAN PROTEIN ATLAS INFORMATION

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RNA tissue category

HPA:Expressed in all
GTEx:Expressed in all

Protein evidence

Evidence at protein level

Protein localization

Most normal cells showed moderate to strong cytoplasmic positivity. Hepatocytes and cells in CNS were generally negative.

ANTIBODY RELIABILITY

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Data reliability
description

Pending RNA-based expert annotation.

Data reliability

Uncertain based on 1 antibody.
CAB004615
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RNA AND PROTEIN EXPRESSION SUMMARY

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RNA expression (FPKM) Protein expression (score)
Brain
Endocrine tissues
Bone marrow & immune system
Muscle tissues
Lung
Liver & gallbladder
Pancreas
Gastrointestinal tract
Kidney & urinary bladder
Male tissues
Female tissues
Adipose & soft tissue
Skin
Cerebral cortex

Lymph node

Liver

Colon

Kidney

Testis



PROTEIN EXPRESSION OVERVIEW

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Organ

Expression



RNA EXPRESSION OVERVIEW

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HPA dataset
RNA tissue category:  Expressed in all

Organ

Expression

GTEx dataset
RNA tissue category:  Expressed in all

Organ

Expression



GENE INFORMATION

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Gene name

ATP6V1G1 (HGNC Symbol)

Synonyms

ATP6G, ATP6G1, ATP6GL, ATP6J, DKFZp547P234, Vma10

Description

ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G1 (HGNC Symbol)

Entrez gene summary

This gene encodes a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles. V-ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation. V-ATPase is composed of a cytosolic V1 domain and a transmembrane V0 domain. The V1 domain consists of three A, three B, and two G subunits, as well as a C, D, E, F, and H subunit. The V1 domain contains the ATP catalytic site. The protein encoded by this gene is one of three V1 domain G subunit proteins. Pseudogenes of this gene have been characterized. [provided by RefSeq, Jul 2008]

Chromosome

9

Cytoband

q32

Chromosome location (bp)

114587746 - 114598373

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000136888 (version 78.38)

Entrez gene

9550

UniProt

O75348 (UniProt - Evidence at protein level)

neXtProt

NX_O75348

Antibodypedia

ATP6V1G1 antibodies


PROTEIN BROWSER

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ENST00000374050
 
 
 
 


PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

ATP6V1G1-001 ENSP00000363162
ENST00000374050
O75348
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