MMP27

GENERAL INFORMATION

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Gene name

MMP27

Gene description

Matrix metallopeptidase 27

Protein class

Enzymes
FDA approved drug targets
Predicted secreted proteins

Predicted localization

Secreted

Number of transcripts

1
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HUMAN PROTEIN ATLAS INFORMATION

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RNA tissue category

HPA:Tissue enhanced (skin)
GTEx:Group enriched (adipose tissue, breast, salivary gland, skin)

Protein evidence

Evidence at protein level

Protein localization

Cytoplasmic expression in a rare subset of lymphoid cells.

ANTIBODY RELIABILITY

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Data reliability
description

Secreted protein, tissue location of RNA and protein might differ and correlation is complex. Pending external verification.

Data reliability

Uncertain based on 1 antibody.
HPA069097
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RNA AND PROTEIN EXPRESSION SUMMARY

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RNA expression (FPKM) Protein expression (score)
Brain
Endocrine tissues
Bone marrow & immune system
Muscle tissues
Lung
Liver & gallbladder
Pancreas
Gastrointestinal tract
Kidney & urinary bladder
Male tissues
Female tissues
Adipose & soft tissue
Skin
Cerebral cortex

Bone marrow

Lymph node

Liver

Colon

Kidney

Testis



PROTEIN EXPRESSION OVERVIEW

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Organ

Expression



RNA EXPRESSION OVERVIEW

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HPA dataset
RNA tissue category:  Tissue enhanced (skin)

Organ

Expression

GTEx dataset
RNA tissue category:  Group enriched (adipose tissue, breast, salivary gland, skin)

Organ

Expression



GENE INFORMATION

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Gene name

MMP27

Synonyms

Description

Matrix metallopeptidase 27 (HGNC Symbol)

Entrez gene summary

Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. [provided by RefSeq, Jul 2008]

Chromosome

11

Cytoband

q22.2

Chromosome location (bp)

102691487 - 102705806

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000137675 (version 78.38)

Entrez gene

64066

UniProt

Q9H306 (UniProt - Evidence at protein level)

neXtProt

NX_Q9H306

Antibodypedia

MMP27 antibodies


PROTEIN BROWSER

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ENST00000260229
 
 
 
 


PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

MMP27-001 ENSP00000260229
ENST00000260229
Q9H306
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