SHF

GENERAL INFORMATION

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Gene name

SHF

Gene description

Src homology 2 domain containing F

Protein class

Predicted intracellular proteins

Predicted localization

Intracellular

Number of transcripts

10
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HUMAN PROTEIN ATLAS INFORMATION

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RNA tissue category

HPA:Mixed
GTEx:Group enriched (cerebellum)

Protein evidence

Evidence at protein level

Protein localization

Respiratory epithelia, stomach, small intestine, Leydig cells and epididymis displayed moderate cytoplasmic positivity. Exocrine pancreas was strongly positive. Remaining normal tissues were weakly stained or negative.

ANTIBODY RELIABILITY

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Data reliability
description

Pending RNA-based expert annotation.

Data reliability

Uncertain based on 1 antibody.
HPA046113
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RNA AND PROTEIN EXPRESSION SUMMARY

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RNA expression (FPKM) Protein expression (score)
Brain
Endocrine tissues
Bone marrow & immune system
Muscle tissues
Lung
Liver & gallbladder
Pancreas
Gastrointestinal tract
Kidney & urinary bladder
Male tissues
Female tissues
Adipose & soft tissue
Skin
Cerebral cortex

Lymph node

Liver

Pancreas

Colon

Kidney

Testis



PROTEIN EXPRESSION OVERVIEW

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Organ

Expression



RNA EXPRESSION OVERVIEW

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HPA dataset
RNA tissue category:  Mixed

Organ

Expression

GTEx dataset
RNA tissue category:  Group enriched (cerebellum)

Organ

Expression



GENE INFORMATION

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Gene name

SHF

Synonyms

Description

Src homology 2 domain containing F (HGNC Symbol)

Entrez gene summary

Chromosome

15

Cytoband

q21.1

Chromosome location (bp)

45167214 - 45201175

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000138606 (version 78.38)

Entrez gene

90525

UniProt

Q7M4L6 (UniProt - Evidence at protein level)

neXtProt

NX_Q7M4L6

Antibodypedia

SHF antibodies


PROTEIN BROWSER

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ENST00000290894
 
ENST00000458022
 
ENST00000558294
 
ENST00000558685
 
ENST00000559566
 
ENST00000560471
 
ENST00000560540
 
ENST00000560734
 
ENST00000561239
 
ENST00000561278
 
 
 
 


PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

SHF-001 ENSP00000290894
ENST00000290894
Q7M4L6
Show all »
Show » Show » 423 46.8 No 0
SHF-002 ENSP00000453370
ENST00000560540
H0YLW6
Show all »
Show » 367 38.2 No 0
SHF-004 ENSP00000453168
ENST00000560734
H0YLD8
Show all »
Show » 290 29.8 No 0
SHF-006 ENSP00000453260
ENST00000560471
H0YLM1
Show all »
Show » 414 43.1 No 0
SHF-008 ENSP00000411530
ENST00000458022
F8W6V4
Show all »
Show » 239 27 No 0
SHF-009 ENSP00000452726
ENST00000559566
H0YNF2
Show all »
Show » 199 22 No 0
SHF-010 ENSP00000453986
ENST00000561278
H0YNF2
Show all »
Show » 26 3 No 0
SHF-011 ENSP00000453827
ENST00000558685
Show » 146 15.6 No 0
SHF-012 ENSP00000454034
ENST00000558294
Show » 163 18.8 No 0
SHF-013 ENSP00000453676
ENST00000561239
Show » 161 17.8 No 0