LPAR6

GENERAL INFORMATION

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Gene name

LPAR6

Gene description

Lysophosphatidic acid receptor 6

Protein class

Disease related genes
G-protein coupled receptors
Potential drug targets
Predicted membrane proteins

Predicted localization

Membrane

Number of transcripts

3
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HUMAN PROTEIN ATLAS INFORMATION

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RNA tissue category

HPA:Expressed in all
GTEx:Expressed in all

Protein evidence

Evidence at protein level

Protein localization

Respiratory epithelia, gastrointestinal tract, exocrine pancreas, urothelial cells and trophoblastic cells showed strong cytoplasmic and membranous staining. Most remaining normal cells were weakly stained or negative.

ANTIBODY RELIABILITY

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Data reliability
description

Pending RNA-based expert annotation.

Data reliability

Uncertain based on 1 antibody.
HPA028934
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RNA AND PROTEIN EXPRESSION SUMMARY

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RNA expression (FPKM) Protein expression (score)
Brain
Endocrine tissues
Bone marrow & immune system
Muscle tissues
Lung
Liver & gallbladder
Pancreas
Gastrointestinal tract
Kidney & urinary bladder
Male tissues
Female tissues
Adipose & soft tissue
Skin
Cerebral cortex

Lymph node

Liver

Colon

Kidney

Testis



PROTEIN EXPRESSION OVERVIEW

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Organ

Expression



RNA EXPRESSION OVERVIEW

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HPA dataset
RNA tissue category:  Expressed in all

Organ

Expression

GTEx dataset
RNA tissue category:  Expressed in all

Organ

Expression



GENE INFORMATION

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Gene name

LPAR6 (HGNC Symbol)

Synonyms

P2RY5, P2Y5

Description

Lysophosphatidic acid receptor 6 (HGNC Symbol)

Entrez gene summary

The protein encoded by this gene belongs to the family of G-protein coupled receptors, that are preferentially activated by adenosine and uridine nucleotides. This gene aligns with an internal intron of the retinoblastoma susceptibility gene in the reverse orientation. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2009]

Chromosome

13

Cytoband

q14.2

Chromosome location (bp)

48389567 - 48444704

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000139679 (version 78.38)

Entrez gene

10161

UniProt

P43657 (UniProt - Evidence at protein level)

neXtProt

NX_P43657

Antibodypedia

LPAR6 antibodies


PROTEIN BROWSER

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ENST00000345941
 
ENST00000378434
 
ENST00000620633
 
 
 
 


PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

LPAR6-001 ENSP00000344353
ENST00000345941
P43657
Show all »
Show » Show » 344 39.4 No 7
LPAR6-003 ENSP00000367691
ENST00000378434
P43657
Show all »
Show » Show » 344 39.4 No 7
LPAR6-201 ENSP00000482660
ENST00000620633
P43657
Show all »
Show » Show » 344 39.4 No 7