SIK1

GENERAL INFORMATION

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Gene name

SIK1

Gene description

Salt-inducible kinase 1

Protein class

Disease related genes
Enzymes
Plasma proteins
Potential drug targets
Predicted membrane proteins

Predicted localization

Membrane

Number of transcripts

1
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HUMAN PROTEIN ATLAS INFORMATION

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RNA tissue category

HPA:Mixed
GTEx:Expressed in all

Protein evidence

Evidence at protein level

Protein localization

General nuclear and cytoplasmic expression.

ANTIBODY RELIABILITY

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Data reliability
description

Antibody staining mainly not consistent with RNA expression data. Caution, targets protein from more than one gene. Pending external verification.

Data reliability

Uncertain based on 2 antibodies.
HPA038211 , CAB023801
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RNA AND PROTEIN EXPRESSION SUMMARY

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RNA expression (FPKM) Protein expression (score)
Brain
Endocrine tissues
Bone marrow & immune system
Muscle tissues
Lung
Liver & gallbladder
Pancreas
Gastrointestinal tract
Kidney & urinary bladder
Male tissues
Female tissues
Adipose & soft tissue
Skin
Cerebral cortex

Lymph node

Liver

Colon

Kidney

Testis



PROTEIN EXPRESSION OVERVIEW

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Organ

Expression



RNA EXPRESSION OVERVIEW

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HPA dataset
RNA tissue category:  Mixed

Organ

Expression

GTEx dataset
RNA tissue category:  Expressed in all

Organ

Expression



GENE INFORMATION

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Gene name

SIK1 (HGNC Symbol)

Synonyms

msk, SNF1LK

Description

Salt-inducible kinase 1 (HGNC Symbol)

Entrez gene summary

Chromosome

21

Cytoband

q22.3

Chromosome location (bp)

43414515 - 43427128

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000142178 (version 78.38)

Entrez gene

150094

UniProt

P57059 (UniProt - Evidence at protein level)

neXtProt

NX_P57059

Antibodypedia

SIK1 antibodies


PROTEIN BROWSER

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ENST00000270162
 
 
 
 


PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

SIK1-001 ENSP00000270162
ENST00000270162
P57059
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