CERS2

GENERAL INFORMATION

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Gene name

CERS2

Gene description

Ceramide synthase 2

Protein class

Predicted membrane proteins

Predicted localization

Membrane

Number of transcripts

9
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HUMAN PROTEIN ATLAS INFORMATION

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RNA tissue category

HPA:Expressed in all
GTEx:Expressed in all

Protein evidence

Evidence at protein level

Protein localization

Normal tissues generally exhibited moderate cytoplasmic positivity. A subset of alveolar cells and gall bladder showed strong immunoreactivity. Neurones were generally weakly stained or negative.

ANTIBODY RELIABILITY

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Data reliability
description

Pending RNA-based expert annotation.

Data reliability

Uncertain based on 1 antibody.
HPA027262
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RNA AND PROTEIN EXPRESSION SUMMARY

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RNA expression (FPKM) Protein expression (score)
Brain
Endocrine tissues
Bone marrow & immune system
Muscle tissues
Lung
Liver & gallbladder
Pancreas
Gastrointestinal tract
Kidney & urinary bladder
Male tissues
Female tissues
Adipose & soft tissue
Skin
Cerebral cortex

Lymph node

Liver

Colon

Kidney

Testis

Placenta



PROTEIN EXPRESSION OVERVIEW

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Organ

Expression



RNA EXPRESSION OVERVIEW

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HPA dataset
RNA tissue category:  Expressed in all

Organ

Expression

GTEx dataset
RNA tissue category:  Expressed in all

Organ

Expression



GENE INFORMATION

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Gene name

CERS2 (HGNC Symbol)

Synonyms

FLJ10243, LASS2, SP260

Description

Ceramide synthase 2 (HGNC Symbol)

Entrez gene summary

This gene encodes a protein that has sequence similarity to yeast longevity assurance gene 1. Mutation or overexpression of the related gene in yeast has been shown to alter yeast lifespan. The human protein may play a role in the regulation of cell growth. Alternatively spliced transcript variants encoding the same protein have been described. [provided by RefSeq, Jul 2008]

Chromosome

1

Cytoband

q21.3

Chromosome location (bp)

150960583 - 150975004

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000143418 (version 78.38)

Entrez gene

29956

UniProt

Q96G23 (UniProt - Evidence at protein level)

neXtProt

NX_Q96G23

Antibodypedia

CERS2 antibodies


PROTEIN BROWSER

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ENST00000271688
 
ENST00000361419
 
ENST00000368949
 
ENST00000368954
 
ENST00000421609
 
ENST00000457392
 
ENST00000558062
 
ENST00000560793
 
ENST00000561294
 
 
 
 


PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

CERS2-001 ENSP00000357950
ENST00000368954
Q96G23
Show all »
Show » Show » 380 44.9 No 6
CERS2-003 ENSP00000357945
ENST00000368949
Q5SZE1
Show all »
Show » Show » 304 36.4 No 6
CERS2-004 ENSP00000355020
ENST00000361419
Q5SZE4
Show all »
Show » Show » 249 29.8 No 4
CERS2-005 ENSP00000394012
ENST00000457392
Q5SZE2
Show all »
Show » Show » 129 15.4 No 1
CERS2-006 ENSP00000393239
ENST00000421609
Q5SZE3
Show all »
Show » Show » 192 23.3 No 2
CERS2-009 ENSP00000452810
ENST00000558062
H0YKH6
Show all »
Show » Show » 223 26.8 No 3
CERS2-012 ENSP00000454160
ENST00000561294
H0YNU7
Show all »
Show » Show » 377 44.5 No 6
CERS2-013 ENSP00000453297
ENST00000560793
Show » Show » 228 26.6 No 4
CERS2-201 ENSP00000271688
ENST00000271688
Q96G23
Show all »
Show » Show » 380 44.9 No 6