SFXN5

GENERAL INFORMATION

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Gene name

SFXN5

Gene description

Sideroflexin 5

Protein class

Mitochondrial proteins
Predicted membrane proteins
Predicted secreted proteins

Predicted localization

Membrane,Secreted

Number of transcripts

4
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HUMAN PROTEIN ATLAS INFORMATION

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RNA tissue category

HPA:Mixed
GTEx:Expressed in all

Protein evidence

Evidence at protein level

Protein localization

Strong and granular cytoplasmic staining in a highly organized pattern in several tissues e.g. gastrointestinal tract, exocrine pancreas and thyroid gland. Skeletal muscle was moderately positive where as the heart muscle displayed distinct staining in intercalated discs. Cells in CNS and lymphoid tissues were virtually negative.

ANTIBODY RELIABILITY

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Data reliability
description

Pending RNA-based expert annotation.

Data reliability

Uncertain based on 1 antibody.
HPA015473
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RNA AND PROTEIN EXPRESSION SUMMARY

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RNA expression (FPKM) Protein expression (score)
Brain
Endocrine tissues
Bone marrow & immune system
Muscle tissues
Lung
Liver & gallbladder
Pancreas
Gastrointestinal tract
Kidney & urinary bladder
Male tissues
Female tissues
Adipose & soft tissue
Skin
Cerebral cortex

Lymph node

Liver

Colon

Kidney

Testis



PROTEIN EXPRESSION OVERVIEW

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Organ

Expression



RNA EXPRESSION OVERVIEW

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HPA dataset
RNA tissue category:  Mixed

Organ

Expression

GTEx dataset
RNA tissue category:  Expressed in all

Organ

Expression



GENE INFORMATION

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Gene name

SFXN5 (HGNC Symbol)

Synonyms

BBG-TCC

Description

Sideroflexin 5 (HGNC Symbol)

Entrez gene summary

Chromosome

2

Cytoband

p13.2

Chromosome location (bp)

72942036 - 73075619

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000144040 (version 78.38)

Entrez gene

94097

UniProt

Q8TD22 (UniProt - Evidence at transcript level)

neXtProt

NX_Q8TD22

Antibodypedia

SFXN5 antibodies


PROTEIN BROWSER

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ENST00000272433
 
ENST00000410065
 
ENST00000411783
 
ENST00000442582
 
 
 
 


PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

SFXN5-001 ENSP00000272433
ENST00000272433
Q8TD22
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Show » Show » 340 37.1 Yes 5
SFXN5-002 ENSP00000387076
ENST00000410065
B8ZZJ6
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Show » Show » 253 28 Yes 1
SFXN5-003 ENSP00000402141
ENST00000411783
Show » Show » 252 27.4 No 2
SFXN5-011 ENSP00000396825
ENST00000442582
C9JIV5
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Show » Show » 156 17.2 Yes 0