Fields »

SUBCELLULAR LOCATION

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Main location(s)

Cytoplasm

Additional location(s)

Plasma membrane 

Staining summary

Mainly localized to cytoplasm but also plasma membrane.

Reliability (APE)

High

Antibodies in assay

HPA019356, HPA029461
 

Antibody HPA019356

 

Antibody HPA029461

 

         Cell line A-431

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Location(s)

Cytoplasm   

Staining characteristics

Granular   

Staining intensity

Moderate   

Validation

One/multiple location(s) supported by experimental gene/protein characterization data.
   

Comment

   

         Cell line U-2 OS

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Location(s)

Cytoplasm Cytoplasm 

Staining characteristics

Granular Granular 

Staining intensity

Moderate Moderate 

Validation

One/multiple location(s) supported by experimental gene/protein characterization data.
 
One/multiple location(s) supported by experimental gene/protein characterization data.
 

Comment

  

         Cell line U-251 MG

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Location(s)

Plasma membrane, Cytoplasm Cytoplasm 

Staining characteristics

 Aggregate 

Staining intensity

Moderate Weak 

Validation

Multiple locations partly supported (at least one) by experimental gene/protein characterization data.
 
One/multiple location(s) supported by experimental gene/protein characterization data.
 

Comment

  

         Antibody summary


Immunofluorescent staining of human cell line U-251MG shows positivity in plasma membrane & cytoplasm.
 

Immunofluorescent staining of human cell line U-251MG shows positivity in cytoplasm.
 

Summary

Staining of cytoplasm in A-431 and U-2 OS. Staining of cytoplasm and plasma membrane in U-251 MG.   Staining of cytoplasm in U-251 MG and U-2 OS.  

Validation

The subcellular location is supported by literature.
 
The subcellular location is supported by literature.
 

Dictionary

Cytoplasm
Plasma membrane