DLG2

GENERAL INFORMATION

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Gene name

DLG2

Gene description

Discs, large homolog 2 (Drosophila)

Protein class

Predicted intracellular proteins

Predicted localization

Intracellular

Number of transcripts

20
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HUMAN PROTEIN ATLAS INFORMATION

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RNA tissue category

HPA:Tissue enhanced (cerebral cortex)
GTEx:Tissue enhanced (cerebral cortex, hippocampus)

Protein evidence

Evidence at protein level

Protein localization

Cytoplasmic expression in CNS.

ANTIBODY RELIABILITY

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Data reliability
description

Antibody staining mainly consistent with RNA expression data.

Data reliability

Uncertain based on 1 antibody.
HPA021307
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RNA AND PROTEIN EXPRESSION SUMMARY

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RNA expression (FPKM) Protein expression (score)
Brain
Endocrine tissues
Bone marrow & immune system
Muscle tissues
Lung
Liver & gallbladder
Pancreas
Gastrointestinal tract
Kidney & urinary bladder
Male tissues
Female tissues
Adipose & soft tissue
Skin
Cerebral cortex

Lymph node

Liver

Colon

Kidney

Testis



PROTEIN EXPRESSION OVERVIEW

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Organ

Expression



RNA EXPRESSION OVERVIEW

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HPA dataset
RNA tissue category:  Tissue enhanced (cerebral cortex)

Organ

Expression

GTEx dataset
RNA tissue category:  Tissue enhanced (cerebral cortex, hippocampus)

Organ

Expression



GENE INFORMATION

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Gene name

DLG2 (HGNC Symbol)

Synonyms

chapsyn-110, PPP1R58, PSD-93, PSD93

Description

Discs, large homolog 2 (Drosophila) (HGNC Symbol)

Entrez gene summary

This gene encodes a member of the membrane-associated guanylate kinase (MAGUK) family. The encoded protein forms a heterodimer with a related family member that may interact at postsynaptic sites to form a multimeric scaffold for the clustering of receptors, ion channels, and associated signaling proteins. Multiple transcript variants encoding different isoforms have been found for this gene. Additional transcript variants have been described, but their full-length nature is not known. [provided by RefSeq, Dec 2008]

Chromosome

11

Cytoband

q14.1

Chromosome location (bp)

83455012 - 85627922

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000150672 (version 78.38)

Entrez gene

1740

UniProt

Q15700 (UniProt - Evidence at protein level)

neXtProt

NX_Q15700

Antibodypedia

DLG2 antibodies


PROTEIN BROWSER

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ENST00000280241
 
ENST00000330014
 
ENST00000376104
 
ENST00000398299
 
ENST00000398301
 
ENST00000398304
 
ENST00000398309
 
ENST00000404783
 
ENST00000418306
 
ENST00000420775
 
ENST00000426717
 
ENST00000434967
 
ENST00000457267
 
ENST00000524601
 
ENST00000524982
 
ENST00000527088
 
ENST00000529399
 
ENST00000530800
 
ENST00000531015
 
ENST00000532653
 
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PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

DLG2-001 ENSP00000381355
ENST00000398309
Q15700
Show all »
Show » Show » 870 97.6 No 0
DLG2-002 ENSP00000381346
ENST00000398301
Q6ZSU2
Show all »
Show » Show » 552 59.3 No 0
DLG2-003 ENSP00000365272
ENST00000376104
Q15700
Show all »
Show » Show » 975 109.4 No 0
DLG2-005 ENSP00000381344
ENST00000398299
A8MUT9
Show all »
Show » Show » 232 25.1 No 0
DLG2-006 ENSP00000403239
ENST00000434967
C9JFF9
Show all »
Show » Show » 108 12.4 No 0
DLG2-007 ENSP00000385113
ENST00000404783
B5MCC5
Show all »
Show » Show » 348 39.9 No 0
DLG2-008 ENSP00000381349
ENST00000398304
A8MVA8
Show all »
Show » Show » 129 14.5 No 0
DLG2-009 ENSP00000435849
ENST00000532653
B7Z2T4
Show all »
Show » Show » 852 95 No 0
DLG2-010 ENSP00000409133
ENST00000457267
H7C325
Show all »
Show » 165 19.4 No 0
DLG2-012 ENSP00000432894
ENST00000524982
E9PN83
Show all »
Show » Show » 866 96.5 No 0
DLG2-013 ENSP00000402275
ENST00000418306
Q15700
Show all »
Show » Show » 749 83.4 No 0
DLG2-014 ENSP00000433848
ENST00000531015
E9PIW2
Show all »
Show » Show » 811 90.7 No 0
DLG2-015 ENSP00000381353
ENST00000330014
B7Z264
Show all »
Show » Show » 791 87.9 No 0
DLG2-016 ENSP00000393049
ENST00000426717
Q15700
Show all »
Show » Show » 334 38.4 No 0
DLG2-017 ENSP00000435809
ENST00000527088
E9PIJ9
Show all »
Show » 74 8.5 No 0
DLG2-020 ENSP00000436302
ENST00000530800
E9PPV7
Show all »
Show » Show » 142 16.3 No 0
DLG2-021 ENSP00000434346
ENST00000529399
E9PQT9
Show all »
Show » Show » 94 10.8 No 0
DLG2-023 ENSP00000436020
ENST00000524601
E9PRL2
Show all »
Show » Show » 109 12.4 No 0
DLG2-024 ENSP00000391017
ENST00000420775
F8W750
Show all »
Show » Show » 221 25.8 No 0
DLG2-201 ENSP00000280241
ENST00000280241
Q15700
Show all »
Show » Show » 909 101 No 0