KIN

GENERAL INFORMATION

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Gene name

KIN

Gene description

Kin17 DNA and RNA binding protein

Protein class

Predicted intracellular proteins

Predicted localization

Intracellular

Number of transcripts

1
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HUMAN PROTEIN ATLAS INFORMATION

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RNA tissue category

HPA:Mixed
GTEx:Expressed in all

Protein evidence

Evidence at protein level

Protein localization

Most of the normal tissues displayed moderate to strong nuclear positivity accompanied with cytoplasmic staining. Cells in seminiferous ducts, prostate glands and alveolar cells were weakly stained or negative.

ANTIBODY RELIABILITY

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Data reliability
description

Pending RNA-based expert annotation.

Data reliability

Uncertain based on 1 antibody.
CAB016339
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RNA AND PROTEIN EXPRESSION SUMMARY

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RNA expression (FPKM) Protein expression (score)
Brain
Endocrine tissues
Bone marrow & immune system
Muscle tissues
Lung
Liver & gallbladder
Pancreas
Gastrointestinal tract
Kidney & urinary bladder
Male tissues
Female tissues
Adipose & soft tissue
Skin
Cerebral cortex

Lymph node

Skeletal muscle

Liver

Colon

Kidney

Testis



PROTEIN EXPRESSION OVERVIEW

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Organ

Expression



RNA EXPRESSION OVERVIEW

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HPA dataset
RNA tissue category:  Mixed

Organ

Expression

GTEx dataset
RNA tissue category:  Expressed in all

Organ

Expression



GENE INFORMATION

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Gene name

KIN (HGNC Symbol)

Synonyms

KIN17, Rts2

Description

Kin17 DNA and RNA binding protein (HGNC Symbol)

Entrez gene summary

The protein encoded by this gene is a nuclear protein that forms intranuclear foci during proliferation and is redistributed in the nucleoplasm during the cell cycle. Short-wave ultraviolet light provokes the relocalization of the protein, suggesting its participation in the cellular response to DNA damage. Originally selected based on protein-binding with RecA antibodies, the mouse protein presents a limited similarity with a functional domain of the bacterial RecA protein, a characteristic shared by this human ortholog. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Jan 2012]

Chromosome

10

Cytoband

p14

Chromosome location (bp)

7750962 - 7787981

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000151657 (version 78.38)

Entrez gene

22944

UniProt

O60870 (UniProt - Evidence at protein level)

neXtProt

NX_O60870

Antibodypedia

KIN antibodies


PROTEIN BROWSER

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ENST00000379562
 
 
 
 


PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

KIN-001 ENSP00000368881
ENST00000379562
O60870
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