CERS3

GENERAL INFORMATION

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Gene name

CERS3

Gene description

Ceramide synthase 3

Protein class

Disease related genes
Enzymes
Potential drug targets
Predicted intracellular proteins
Predicted membrane proteins

Predicted localization

Intracellular,Membrane

Number of transcripts

5
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HUMAN PROTEIN ATLAS INFORMATION

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RNA tissue category

HPA:Group enriched (esophagus, skin, testis, tonsil)
GTEx:Group enriched (cervix, uterine, esophagus, skin, testis, vagina)

Protein evidence

Evidence at protein level

Protein localization

RNA data suggests expression in a selected group of tissues, most abundant in skin. RNA-based expert annotation could not be performed.

ANTIBODY RELIABILITY

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Data reliability
description

Pending external verification. Presumed off target binding observed and disregarded.

Data reliability

Uncertain based on 2 antibodies.
HPA006092 , HPA024356
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RNA AND PROTEIN EXPRESSION SUMMARY

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RNA expression (FPKM) Protein expression (score)
Brain
N/A
Endocrine tissues
N/A
Bone marrow & immune system
N/A
Muscle tissues
N/A
Lung
N/A
Nasopharynx
N/A
N/A
Bronchus
N/A
N/A
Lung
N/A
Liver & gallbladder
N/A
Liver
N/A
Pancreas
N/A
Pancreas
N/A
Gastrointestinal tract
N/A
Kidney & urinary bladder
N/A
Male tissues
N/A
Testis
N/A
Epididymis
N/A
N/A
Prostate
N/A
Seminal vesicle
N/A
N/A
Female tissues
N/A
Breast
N/A
N/A
Vagina
N/A
N/A
Cervix, uterine
N/A
N/A
Ovary
N/A
Placenta
N/A
Adipose & soft tissue
N/A
Skin
N/A
Skin
N/A
Cerebral cortex

Lymph node

Liver

Colon

Kidney

Testis



PROTEIN EXPRESSION OVERVIEW

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RNA-based expert annotation could not be performed, due to inconclusive results. View immunohistochemistry primary data.


RNA EXPRESSION OVERVIEW

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HPA dataset
RNA tissue category:  Group enriched (esophagus, skin, testis, tonsil)

Organ

Expression

GTEx dataset
RNA tissue category:  Group enriched (cervix, uterine, esophagus, skin, testis, vagina)

Organ

Expression



GENE INFORMATION

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Gene name

CERS3 (HGNC Symbol)

Synonyms

LASS3, MGC27091

Description

Ceramide synthase 3 (HGNC Symbol)

Entrez gene summary

Chromosome

15

Cytoband

q26.3

Chromosome location (bp)

100400395 - 100544995

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000154227 (version 78.38)

Entrez gene

204219

UniProt

Q8IU89 (UniProt - Evidence at protein level)

neXtProt

NX_Q8IU89

Antibodypedia

CERS3 antibodies


PROTEIN BROWSER

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ENST00000284382
 
ENST00000394113
 
ENST00000538112
 
ENST00000558884
 
ENST00000559639
 
 
 
 


PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

CERS3-001 ENSP00000284382
ENST00000284382
Q8IU89
Show all »
Show » Show » 383 46.3 No 7
CERS3-002 ENSP00000377672
ENST00000394113
Q8IU89
Show all »
Show » Show » 383 46.3 No 7
CERS3-004 ENSP00000453816
ENST00000558884
H0YN05
Show all »
Show » Show » 162 19.7 No 2
CERS3-005 ENSP00000437640
ENST00000538112
Q8IU89
Show all »
Show » Show » 383 46.3 No 7
CERS3-006 ENSP00000453598
ENST00000559639
H0YMG6
Show all »
Show » 15 2.2 No 0