ABCA9

GENERAL INFORMATION

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Gene name

ABCA9

Gene description

ATP-binding cassette, sub-family A (ABC1), member 9

Protein class

Predicted membrane proteins
Transporters

Predicted localization

Membrane

Number of transcripts

4
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HUMAN PROTEIN ATLAS INFORMATION

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RNA tissue category

HPA:Tissue enhanced (ovary)
GTEx:Expressed in all

Protein evidence

Evidence at protein level

Protein localization

Ubiquitous nuclear expression.

ANTIBODY RELIABILITY

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Data reliability
description

Antibody staining mainly not consistent with RNA expression data. Pending external verification.

Data reliability

Uncertain based on 1 antibody.
HPA054823
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RNA AND PROTEIN EXPRESSION SUMMARY

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RNA expression (FPKM) Protein expression (score)
Brain
Endocrine tissues
Bone marrow & immune system
Muscle tissues
Lung
Liver & gallbladder
Pancreas
Gastrointestinal tract
Kidney & urinary bladder
Male tissues
Female tissues
Adipose & soft tissue
Skin
Cerebral cortex

Lymph node

Liver

Colon

Kidney

Testis

Ovary



PROTEIN EXPRESSION OVERVIEW

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Organ

Expression



RNA EXPRESSION OVERVIEW

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HPA dataset
RNA tissue category:  Tissue enhanced (ovary)

Organ

Expression

GTEx dataset
RNA tissue category:  Expressed in all

Organ

Expression



GENE INFORMATION

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Gene name

ABCA9 (HGNC Symbol)

Synonyms

EST640918

Description

ATP-binding cassette, sub-family A (ABC1), member 9 (HGNC Symbol)

Entrez gene summary

This gene is a member of the superfamily of ATP-binding cassette (ABC) transporters and the encoded protein contains two transmembrane domains and two nucleotide binding folds. ABC proteins transport various molecules across extra- and intracellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, and White). This gene is a member of the ABC1 subfamily and is clustered with four other ABC1 family members on chromosome 17q24. Transcriptional expression of this gene is induced during monocyte differentiation into macrophages and is suppressed by cholesterol import. [provided by RefSeq, Jul 2008]

Chromosome

17

Cytoband

q24.2

Chromosome location (bp)

68974488 - 69061064

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000154258 (version 78.38)

Entrez gene

10350

UniProt

Q8IUA7 (UniProt - Evidence at protein level)

neXtProt

NX_Q8IUA7

Antibodypedia

ABCA9 antibodies


PROTEIN BROWSER

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ENST00000340001
 
ENST00000453985
 
ENST00000495634
 
ENST00000585714
 
 
 
 


PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

ABCA9-001 ENSP00000342216
ENST00000340001
Q8IUA7
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Show » Show » 1624 184.4 No >9
ABCA9-002 ENSP00000394264
ENST00000453985
H0Y4U7
Show all »
Show » Show » 1586 180 No >9
ABCA9-003 ENSP00000465601
ENST00000495634
Q8IUA7
Show all »
Show » Show » 267 31 No 2
ABCA9-008 ENSP00000465191
ENST00000585714
K7EJJ0
Show all »
Show » 89 10.6 No 1