CPA5

GENERAL INFORMATION

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Gene name

CPA5

Gene description

Carboxypeptidase A5

Protein class

Enzymes
Predicted intracellular proteins

Predicted localization

Intracellular

Number of transcripts

10
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HUMAN PROTEIN ATLAS INFORMATION

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RNA tissue category

HPA:Tissue enriched (testis)
GTEx:Tissue enriched (testis)

Protein evidence

Evidence at protein level

Protein localization

RNa data suggests expression in testis. RNA-based expert annotation gave inconclusive results.

ANTIBODY RELIABILITY

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Data reliability
description

Pending external verification. Presumed off target binding observed and disregarded.

Data reliability

Uncertain based on 1 antibody.
HPA020322
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RNA AND PROTEIN EXPRESSION SUMMARY

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RNA expression (FPKM) Protein expression (score)
Brain
N/A
Endocrine tissues
N/A
Bone marrow & immune system
N/A
Muscle tissues
N/A
Lung
N/A
Nasopharynx
N/A
N/A
Bronchus
N/A
N/A
Lung
N/A
Liver & gallbladder
N/A
Liver
N/A
Pancreas
N/A
Pancreas
N/A
Gastrointestinal tract
N/A
Kidney & urinary bladder
N/A
Male tissues
N/A
Testis
N/A
Epididymis
N/A
N/A
Prostate
N/A
Seminal vesicle
N/A
N/A
Female tissues
N/A
Breast
N/A
N/A
Vagina
N/A
N/A
Cervix, uterine
N/A
N/A
Ovary
N/A
Placenta
N/A
Adipose & soft tissue
N/A
Skin
N/A
Skin
N/A
Cerebral cortex

Lymph node

Liver

Colon

Kidney

Testis



PROTEIN EXPRESSION OVERVIEW

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RNA-based expert annotation could not be performed, due to inconclusive results. View immunohistochemistry primary data.


RNA EXPRESSION OVERVIEW

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HPA dataset
RNA tissue category:  Tissue enriched (testis)

Organ

Expression

GTEx dataset
RNA tissue category:  Tissue enriched (testis)

Organ

Expression



GENE INFORMATION

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Gene name

CPA5

Synonyms

Description

Carboxypeptidase A5 (HGNC Symbol)

Entrez gene summary

Carboxypeptidases have functions ranging from digestion of food to selective biosynthesis of neuroendocrine peptides. Members of the A/B subfamily of carboxypeptidases, such as CPA5, contain an approximately 90-amino acid pro region that assists in the folding of the active carboxypeptidase domain. Cleavage of the pro region activates the enzyme (Wei et al., 2002 [PubMed 11836249]).[supplied by OMIM, Mar 2008]

Chromosome

7

Cytoband

q32.2

Chromosome location (bp)

130344816 - 130368730

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000158525 (version 78.38)

Entrez gene

93979

UniProt

Q8WXQ8 (UniProt - Evidence at transcript level)

neXtProt

NX_Q8WXQ8

Antibodypedia

CPA5 antibodies


PROTEIN BROWSER

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ENST00000393213
 
ENST00000431780
 
ENST00000461828
 
ENST00000463587
 
ENST00000466363
 
ENST00000474905
 
ENST00000479492
 
ENST00000485477
 
ENST00000494311
 
ENST00000497503
 
 
 
 


PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

CPA5-001 ENSP00000420237
ENST00000485477
Q8WXQ8
Show all »
Show » Show » 436 49 No 0
CPA5-003 ENSP00000376907
ENST00000393213
Q8WXQ8
Show all »
Show » Show » 436 49 No 0
CPA5-005 ENSP00000417314
ENST00000474905
Q8WXQ8
Show all »
Show » Show » 436 49 No 0
CPA5-006 ENSP00000419025
ENST00000466363
Q8WXQ8
Show all »
Show » Show » 436 49 No 0
CPA5-007 ENSP00000393045
ENST00000431780
Q8WXQ8
Show all »
Show » Show » 403 44.9 No 0
CPA5-008 ENSP00000418183
ENST00000461828
Q8WXQ8
Show all »
Show » Show » 436 49 No 0
CPA5-010 ENSP00000420060
ENST00000463587
C9JRV5
Show all »
Show » Show » 123 13.6 No 0
CPA5-011 ENSP00000419013
ENST00000497503
Show » 8 0.7 No 0
CPA5-012 ENSP00000419778
ENST00000494311
C9JZE9
Show all »
Show » 32 3.3 No 0
CPA5-013 ENSP00000417886
ENST00000479492
Show » Show » 85 9.5 No 0