The primary data page shows the detailed antibody staining in 76 different cell types for each analyzed antibody. In addition, for each cell type, a knowledge-based annotated protein expression score based on all analyzed antibodies is displayed furthest to the right. The images and annotations can be accessed by clicking on the tissue name or score bar. More information can be found in Assays & Annotation.
The tissues and cell types can be ordered by organ, cell type or alphabetically. If ordered by organ, the tissues are presented in groups according to functional features. If ordered by cell type, the cells are presented in groups related to origin.
This score describes the level of antibody staining observed in the annotated cell types as not detected (n), low (l), medium (m) or high (h). It is based on the staining intensity and fraction of stained cells. The images and annotations can be accessed by clicking on the tissue name or score bar. More information can be found in Assays & Annotation.
This score describes a knowledge-based best estimate of the protein expression in the annotated cell types as not detected (n), low (l), medium (m) or high (h). It is a result of stringent evaluation of immunohistochemical staining pattern, RNA data from internal and external sources and available protein/gene characterization data. More information can be found in Assays & Annotation.
Summarizing texts describe the staining pattern for each antibody based on staining intensity, fraction of stained cells and subcellular localization. More information can be found in Assays & Annotation.
A subset of cells in red pulp of spleen and bone marrow displayed strong cytoplasmic immunoreactivity. Remaining normal cells were negative.
Hematopoietic cells of bone marrow and subset of cells in spleen showed strong cytoplasmic positivity while distinct cytoplasmic and membranous immunoreactivity was seen in epididymis. Stomach, exocrine pancreas, adrenal gland, renal tubules, cells in seminiferous ducts of testis, seminal vesicle, cells of CNS and skeletal myocytes showed moderate cytoplasmic positivity. Remaining normal tissues were negative.
Strong cytoplasmic positivity was observed in subset of cells in bone marrow and red pulp of spleen. Salivary ducts, gastrointestinal tract, parathyroid, renal tubules, cardiac myocytes and Purkinje cells exhibited moderate staining. Leydig cells showed strong cytoplasmic and nuclear staining. Remaining normal tissues were weakly stained or negative.