BRWD3

GENERAL INFORMATION

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Gene name

BRWD3

Gene description

Bromodomain and WD repeat domain containing 3

Protein class

Disease related genes
Predicted intracellular proteins

Predicted localization

Intracellular

Number of transcripts

1
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HUMAN PROTEIN ATLAS INFORMATION

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RNA tissue category

HPA:Mixed
GTEx:Expressed in all

Protein evidence

Evidence at protein level

Protein localization

Most normal tissues displayed weak to moderate cytoplasmic positivity. Membranous positivity was detected in several glandular epithelia as well as in pneumocytes.

ANTIBODY RELIABILITY

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Data reliability
description

Pending RNA-based expert annotation.

Data reliability

Uncertain based on 1 antibody.
HPA012802
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RNA AND PROTEIN EXPRESSION SUMMARY

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RNA expression (FPKM) Protein expression (score)
Brain
Endocrine tissues
Bone marrow & immune system
Muscle tissues
Lung
Liver & gallbladder
Pancreas
Gastrointestinal tract
Kidney & urinary bladder
Male tissues
Female tissues
Adipose & soft tissue
Skin
Cerebral cortex

Lymph node

Liver

Colon

Kidney

Testis



PROTEIN EXPRESSION OVERVIEW

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Organ

Expression



RNA EXPRESSION OVERVIEW

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HPA dataset
RNA tissue category:  Mixed

Organ

Expression

GTEx dataset
RNA tissue category:  Expressed in all

Organ

Expression



GENE INFORMATION

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Gene name

BRWD3 (HGNC Symbol)

Synonyms

FLJ38568, MRX93

Description

Bromodomain and WD repeat domain containing 3 (HGNC Symbol)

Entrez gene summary

The protein encoded by this gene contains a bromodomain and several WD repeats. It is thought to have a chromatin-modifying function, and may thus play a role in transcription. Mutations in this gene cause mental retardation X-linked type 93, which is also referred to as mental retardation X-linked with macrocephaly. This gene is also associated with translocations in patients with B-cell chronic lymphocytic leukemia. [provided by RefSeq, May 2010]

Chromosome

X

Cytoband

q21.1

Chromosome location (bp)

80670854 - 80809688

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000165288 (version 78.38)

Entrez gene

254065

UniProt

Q6RI45 (UniProt - Evidence at protein level)

neXtProt

NX_Q6RI45

Antibodypedia

BRWD3 antibodies


PROTEIN BROWSER

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ENST00000373275
 
 
 
 


PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

BRWD3-001 ENSP00000362372
ENST00000373275
Q6RI45
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