ENOX2

GENERAL INFORMATION

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Gene name

ENOX2

Gene description

Ecto-NOX disulfide-thiol exchanger 2

Protein class

Predicted intracellular proteins

Predicted localization

Intracellular

Number of transcripts

6
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HUMAN PROTEIN ATLAS INFORMATION

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RNA tissue category

HPA:Expressed in all
GTEx:Expressed in all

Protein evidence

Evidence at protein level

Protein localization

Smooth muscle cells and glandular cells in stomach showed strong cytoplasmic positivity. Remaining normal cells were generally negative.

ANTIBODY RELIABILITY

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Data reliability
description

Pending RNA-based expert annotation.

Data reliability

Uncertain based on 1 antibody.
HPA000514
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RNA AND PROTEIN EXPRESSION SUMMARY

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RNA expression (FPKM) Protein expression (score)
Brain
Endocrine tissues
Bone marrow & immune system
Muscle tissues
Lung
Liver & gallbladder
Pancreas
Gastrointestinal tract
Kidney & urinary bladder
Male tissues
Female tissues
Adipose & soft tissue
Skin
Cerebral cortex

Lymph node

Liver

Stomach

Colon

Kidney

Testis



PROTEIN EXPRESSION OVERVIEW

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Organ

Expression



RNA EXPRESSION OVERVIEW

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HPA dataset
RNA tissue category:  Expressed in all

Organ

Expression

GTEx dataset
RNA tissue category:  Expressed in all

Organ

Expression



GENE INFORMATION

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Gene name

ENOX2 (HGNC Symbol)

Synonyms

APK1, COVA1, tNOX

Description

Ecto-NOX disulfide-thiol exchanger 2 (HGNC Symbol)

Entrez gene summary

This gene is a tumor-specific member of the ECTO-NOX family of genes that encode cell surface NADH oxidases. The encoded protein has two enzymatic activities: catalysis of hydroquinone or NADH oxidation, and protein disulfide interchange. The protein also displays prion-like properties. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2013]

Chromosome

X

Cytoband

q26.1

Chromosome location (bp)

130623369 - 130903317

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000165675 (version 78.38)

Entrez gene

10495

UniProt

Q16206 (UniProt - Evidence at protein level)

neXtProt

NX_Q16206

Antibodypedia

ENOX2 antibodies


PROTEIN BROWSER

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ENST00000338144
 
ENST00000370927
 
ENST00000370935
 
ENST00000394363
 
ENST00000432489
 
ENST00000610637
 
 
 
 


PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

ENOX2-002 ENSP00000400304
ENST00000432489
B1AKF7
Show all »
Show » Show » 376 42.9 No 0
ENOX2-003 ENSP00000359973
ENST00000370935
Q16206
Show all »
Show » Show » 581 66.6 No 0
ENOX2-004 ENSP00000359965
ENST00000370927
Q16206
Show all »
Show » Show » 610 70.1 No 0
ENOX2-201 ENSP00000337146
ENST00000338144
Q16206
Show all »
Show » Show » 610 70.1 No 0
ENOX2-202 ENSP00000377890
ENST00000394363
Q16206
Show all »
Show » Show » 581 66.6 No 0
ENOX2-203 ENSP00000478608
ENST00000610637
Q16206
Show all »
Show » Show » 263 30.5 No 0