TMEM55B

GENERAL INFORMATION

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Gene name

TMEM55B

Gene description

Transmembrane protein 55B

Protein class

Enzymes
Predicted intracellular proteins
Predicted membrane proteins

Predicted localization

Intracellular,Membrane

Number of transcripts

5
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HUMAN PROTEIN ATLAS INFORMATION

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RNA tissue category

HPA:Expressed in all
GTEx:Expressed in all

Protein evidence

Evidence at protein level

Protein localization

Most normal tissues displayed moderate cytoplasmic and/or nuclear positivity. Renal tubules, cardiac myocytes, hepatocytes and exocrine pancreas displayed strong immunoreactivity.

ANTIBODY RELIABILITY

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Data reliability
description

Pending RNA-based expert annotation.

Data reliability

Uncertain based on 1 antibody.
HPA048528
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RNA AND PROTEIN EXPRESSION SUMMARY

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RNA expression (FPKM) Protein expression (score)
Brain
Endocrine tissues
Bone marrow & immune system
Muscle tissues
Lung
Bronchus
N/A
N/A
Liver & gallbladder
Pancreas
Gastrointestinal tract
Kidney & urinary bladder
Male tissues
Female tissues
Adipose & soft tissue
Skin
Cerebral cortex

Lymph node

Liver

Colon

Kidney

Testis

Skin



PROTEIN EXPRESSION OVERVIEW

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Organ

Expression



RNA EXPRESSION OVERVIEW

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HPA dataset
RNA tissue category:  Expressed in all

Organ

Expression

GTEx dataset
RNA tissue category:  Expressed in all

Organ

Expression



GENE INFORMATION

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Gene name

TMEM55B (HGNC Symbol)

Synonyms

C14orf9, MGC26684

Description

Transmembrane protein 55B (HGNC Symbol)

Entrez gene summary

TMEM55B catalyzes the degradation of phosphatidylinositol 4,5-bisphosphate (PtdIns-4,5-P2) by removing the 4-phosphate (Ungewickell et al., 2005 [PubMed 16365287]).[supplied by OMIM, Mar 2008]

Chromosome

14

Cytoband

q11.2

Chromosome location (bp)

20457719 - 20461612

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000165782 (version 78.38)

Entrez gene

90809

UniProt

Q86T03 (UniProt - Evidence at protein level)

neXtProt

NX_Q86T03

Antibodypedia

TMEM55B antibodies


PROTEIN BROWSER

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ENST00000250489
 
ENST00000398020
 
ENST00000553460
 
ENST00000554028
 
ENST00000556093
 
 
 
 


PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

TMEM55B-001 ENSP00000250489
ENST00000250489
Q86T03
Show all »
Show » Show » 277 29.5 No 2
TMEM55B-003 ENSP00000381102
ENST00000398020
Q86T03
Show all »
Show » Show » 284 30.2 No 2
TMEM55B-004 ENSP00000452508
ENST00000556093
G3V5T5
Show all »
Show » 44 4.9 No 0
TMEM55B-005 ENSP00000451350
ENST00000554028
G3V3P3
Show all »
Show » 110 12.5 No 2
TMEM55B-007 ENSP00000451014
ENST00000553460
Show » 112 12.5 No 2