CMTM5

GENERAL INFORMATION

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Gene name

CMTM5

Gene description

CKLF-like MARVEL transmembrane domain containing 5

Protein class

Predicted membrane proteins

Predicted localization

Membrane

Number of transcripts

6
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HUMAN PROTEIN ATLAS INFORMATION

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RNA tissue category

HPA:Tissue enriched (cerebral cortex)
GTEx:Tissue enhanced (heart muscle, hippocampus)

Protein evidence

Evidence at protein level

Protein localization

Selective expression in CNS and peripheral nerves.

ANTIBODY RELIABILITY

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Data reliability
description

Antibody staining mainly consistent with RNA expression data.

Data reliability

Supportive based on 1 antibody.
HPA052338
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RNA AND PROTEIN EXPRESSION SUMMARY

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RNA expression (FPKM) Protein expression (score)
Brain
Endocrine tissues
Bone marrow & immune system
Muscle tissues
Lung
Nasopharynx
N/A
N/A
Bronchus
N/A
Liver & gallbladder
Pancreas
Gastrointestinal tract
Kidney & urinary bladder
Male tissues
Female tissues
Adipose & soft tissue
Skin
Cerebral cortex

Hippocampus

Lymph node

Liver

Colon

Kidney

Testis



PROTEIN EXPRESSION OVERVIEW

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Organ

Expression



RNA EXPRESSION OVERVIEW

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HPA dataset
RNA tissue category:  Tissue enriched (cerebral cortex)

Organ

Expression

GTEx dataset
RNA tissue category:  Tissue enhanced (heart muscle, hippocampus)

Organ

Expression



GENE INFORMATION

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Gene name

CMTM5 (HGNC Symbol)

Synonyms

CKLFSF5, FLJ37521

Description

CKLF-like MARVEL transmembrane domain containing 5 (HGNC Symbol)

Entrez gene summary

This gene encodes a member of the chemokine-like factor superfamily. This family of genes encodes multi-pass membrane proteins that are similar to both the chemokine and the transmembrane 4 superfamilies of signaling molecules. The encoded protein may exhibit tumor suppressor activity. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2014]

Chromosome

14

Cytoband

q11.2

Chromosome location (bp)

23376808 - 23379772

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000166091 (version 78.38)

Entrez gene

116173

UniProt

Q96DZ9 (UniProt - Evidence at transcript level)

neXtProt

NX_Q96DZ9

Antibodypedia

CMTM5 antibodies


PROTEIN BROWSER

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ENST00000339180
 
ENST00000342473
 
ENST00000359320
 
ENST00000382809
 
ENST00000397227
 
ENST00000555731
 
 
 
 


PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

CMTM5-001 ENSP00000352270
ENST00000359320
Q96DZ9
Show all »
Show » Show » 156 17.4 No 3
CMTM5-003 ENSP00000344819
ENST00000339180
Q96DZ9
Show all »
Show » Show » 223 24.7 No 4
CMTM5-004 ENSP00000344160
ENST00000342473
Q96DZ9
Show all »
Show » Show » 74 8.3 No 1
CMTM5-005 ENSP00000380404
ENST00000397227
Q96DZ9
Show all »
Show » Show » 105 11.5 No 2
CMTM5-007 ENSP00000451514
ENST00000555731
C9JAI6
Show all »
Show » 118 13.2 No 2
CMTM5-009 ENSP00000372259
ENST00000382809
Q96DZ9
Show all »
Show » Show » 125 14.2 No 2