ADAMTS15

GENERAL INFORMATION

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Gene name

ADAMTS15

Gene description

ADAM metallopeptidase with thrombospondin type 1 motif, 15

Protein class

Enzymes
Predicted secreted proteins

Predicted localization

Secreted

Number of transcripts

1
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HUMAN PROTEIN ATLAS INFORMATION

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RNA tissue category

HPA:Tissue enhanced (adipose tissue, placenta)
GTEx:Mixed

Protein evidence

Evidence at transcript level

Protein localization

External data suggests expression in fetal tissues. RNA-based expert annotation gave inconclusive results.

ANTIBODY RELIABILITY

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Data reliability
description

Antibody staining mainly not consistent with RNA expression data. Pending external verification.

Data reliability

Uncertain based on 1 antibody.
HPA042867
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RNA AND PROTEIN EXPRESSION SUMMARY

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RNA expression (FPKM) Protein expression (score)
Brain
N/A
Endocrine tissues
N/A
Bone marrow & immune system
N/A
Muscle tissues
N/A
Lung
N/A
Nasopharynx
N/A
N/A
Bronchus
N/A
N/A
Lung
N/A
Liver & gallbladder
N/A
Liver
N/A
Pancreas
N/A
Pancreas
N/A
Gastrointestinal tract
N/A
Kidney & urinary bladder
N/A
Male tissues
N/A
Testis
N/A
Epididymis
N/A
N/A
Prostate
N/A
Seminal vesicle
N/A
N/A
Female tissues
N/A
Breast
N/A
N/A
Vagina
N/A
N/A
Cervix, uterine
N/A
N/A
Ovary
N/A
Placenta
N/A
Adipose & soft tissue
N/A
Skin
N/A
Skin
N/A
Cerebral cortex

Lymph node

Liver

Colon

Kidney

Testis



PROTEIN EXPRESSION OVERVIEW

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RNA-based expert annotation could not be performed, due to inconclusive results. View immunohistochemistry primary data.


RNA EXPRESSION OVERVIEW

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HPA dataset
RNA tissue category:  Tissue enhanced (adipose tissue, placenta)

Organ

Expression

GTEx dataset
RNA tissue category:  Mixed

Organ

Expression



GENE INFORMATION

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Gene name

ADAMTS15

Synonyms

Description

ADAM metallopeptidase with thrombospondin type 1 motif, 15 (HGNC Symbol)

Entrez gene summary

This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) protein family. ADAMTS family members share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The protein encoded by this gene has a high sequence similarity to the proteins encoded by ADAMTS1 and ADAMTS8. [provided by RefSeq, Jul 2008]

Chromosome

11

Cytoband

q24.3

Chromosome location (bp)

130448974 - 130476641

Protein evidence

Evidence at transcript level (all genes)

Ensembl

ENSG00000166106 (version 78.38)

Entrez gene

170689

UniProt

Q8TE58 (UniProt - Evidence at transcript level)

neXtProt

NX_Q8TE58

Antibodypedia

ADAMTS15 antibodies


PROTEIN BROWSER

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ENST00000299164
 
 
 
 


PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

ADAMTS15-001 ENSP00000299164
ENST00000299164
Q8TE58
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