MS4A7

GENERAL INFORMATION

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Gene name

MS4A7

Gene description

Membrane-spanning 4-domains, subfamily A, member 7

Protein class

Predicted intracellular proteins
Predicted membrane proteins

Predicted localization

Intracellular,Membrane

Number of transcripts

7
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HUMAN PROTEIN ATLAS INFORMATION

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RNA tissue category

HPA:Tissue enhanced (spleen)
GTEx:Tissue enhanced (spleen)

Protein evidence

Evidence at protein level

Protein localization

Cytoplasmic expression in all tissues at variable levels. Highest expression in gastrointestinal tract.

ANTIBODY RELIABILITY

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Data reliability
description

Pending RNA-based expert annotation.

Data reliability

Uncertain based on 2 antibodies.
HPA017418 , CAB026387
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RNA AND PROTEIN EXPRESSION SUMMARY

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RNA expression (FPKM) Protein expression (score)
Brain
Endocrine tissues
Bone marrow & immune system
Muscle tissues
Lung
Liver & gallbladder
Pancreas
Gastrointestinal tract
Kidney & urinary bladder
Male tissues
Female tissues
Adipose & soft tissue
Skin
Cerebral cortex

Lymph node

Liver

Colon

Kidney

Testis



PROTEIN EXPRESSION OVERVIEW

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Organ

Expression



RNA EXPRESSION OVERVIEW

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HPA dataset
RNA tissue category:  Tissue enhanced (spleen)

Organ

Expression

GTEx dataset
RNA tissue category:  Tissue enhanced (spleen)

Organ

Expression



GENE INFORMATION

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Gene name

MS4A7 (HGNC Symbol)

Synonyms

CD20L4, CFFM4, MS4A8

Description

Membrane-spanning 4-domains, subfamily A, member 7 (HGNC Symbol)

Entrez gene summary

This gene encodes a member of the membrane-spanning 4A gene family, members of which are characterized by common structural features and similar intron/exon splice boundaries and display unique expression patterns in hematopoietic cells and nonlymphoid tissues. This family member is associated with mature cellular function in the monocytic lineage, and it may be a component of a receptor complex involved in signal transduction. This gene is localized to 11q12, in a cluster of other family members. At least four alternatively spliced transcript variants encoding two distinct isoforms have been observed. [provided by RefSeq, Jul 2008]

Chromosome

11

Cytoband

q12.2

Chromosome location (bp)

60378482 - 60395951

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000166927 (version 78.38)

Entrez gene

58475

UniProt

Q9GZW8 (UniProt - Evidence at protein level)

neXtProt

NX_Q9GZW8

Antibodypedia

MS4A7 antibodies


PROTEIN BROWSER

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ENST00000300184
 
ENST00000358246
 
ENST00000528215
 
ENST00000530027
 
ENST00000530234
 
ENST00000530614
 
ENST00000534016
 
 
 
 


PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

MS4A7-001 ENSP00000300184
ENST00000300184
Q9GZW8
Show all »
Show » Show » 240 26.1 No 4
MS4A7-002 ENSP00000434637
ENST00000534016
Q9GZW8
Show all »
Show » Show » 195 21.4 No 2
MS4A7-005 ENSP00000433861
ENST00000530614
E9PIV6
Show all »
Show » Show » 169 18.5 No 2
MS4A7-009 ENSP00000431408
ENST00000528215
E9PL98
Show all »
Show » 39 4.2 No 0
MS4A7-010 ENSP00000433184
ENST00000530234
E9PM26
Show all »
Show » Show » 98 10.6 No 1
MS4A7-011 ENSP00000434819
ENST00000530027
E9PN40
Show all »
Show » Show » 161 17.7 No 2
MS4A7-201 ENSP00000350983
ENST00000358246
Q9GZW8
Show all »
Show » Show » 195 21.4 No 2