MTCL1

GENERAL INFORMATION

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Gene name

MTCL1

Gene description

Microtubule crosslinking factor 1

Protein class

Cytoskeleton related proteins
Plasma proteins
Predicted intracellular proteins

Predicted localization

Intracellular

Number of transcripts

6
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HUMAN PROTEIN ATLAS INFORMATION

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RNA tissue category

HPA:Mixed
GTEx:Group enriched (cerebellum)

Protein evidence

Evidence at protein level

Protein localization

Most normal tissues displayed weak to moderate nuclear and cytoplasmic positivity. Membranous staining was observed in a few cases. Hematopoietic cells and superficial layer of squamous epithelia exhibited strong immunoreactivity. Breast, adrenal gland, glial cells and lymphoid tissues were in general weakly stained or negative.

ANTIBODY RELIABILITY

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Data reliability
description

Pending RNA-based expert annotation.

Data reliability

Uncertain based on 1 antibody.
HPA046245
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RNA AND PROTEIN EXPRESSION SUMMARY

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RNA expression (FPKM) Protein expression (score)
Brain
Endocrine tissues
Bone marrow & immune system
Muscle tissues
Lung
Liver & gallbladder
Pancreas
Gastrointestinal tract
Kidney & urinary bladder
Male tissues
Female tissues
Adipose & soft tissue
Skin
Cerebral cortex

Bone marrow

Lymph node

Liver

Colon

Kidney

Testis



PROTEIN EXPRESSION OVERVIEW

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Organ

Expression



RNA EXPRESSION OVERVIEW

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HPA dataset
RNA tissue category:  Mixed

Organ

Expression

GTEx dataset
RNA tissue category:  Group enriched (cerebellum)

Organ

Expression



GENE INFORMATION

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Gene name

MTCL1 (HGNC Symbol)

Synonyms

CCDC165, KIAA0802, SOGA2

Description

Microtubule crosslinking factor 1 (HGNC Symbol)

Entrez gene summary

Chromosome

18

Cytoband

p11.22

Chromosome location (bp)

8705661 - 8832778

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000168502 (version 78.38)

Entrez gene

23255

UniProt

Q9Y4B5 (UniProt - Evidence at protein level)

neXtProt

NX_Q9Y4B5

Antibodypedia

MTCL1 antibodies


PROTEIN BROWSER

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ENST00000306329
 
ENST00000359865
 
ENST00000400050
 
ENST00000517570
 
ENST00000518815
 
ENST00000523122
 
 
 
 


PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

MTCL1-001 ENSP00000352927
ENST00000359865
Q9Y4B5
Show all »
Show » Show » 1586 177.9 No 0
MTCL1-003 ENSP00000429556
ENST00000517570
Q9Y4B5
Show all »
Show » Show » 1545 173.3 No 0
MTCL1-006 ENSP00000463465
ENST00000518815
Q9Y4B5
Show all »
Show » Show » 976 108.7 No 0
MTCL1-007 ENSP00000463506
ENST00000523122
J3QLE1
Show all »
Show » 47 5.9 No 0
MTCL1-015 ENSP00000305027
ENST00000306329
Q9Y4B5
Show all »
Show » Show » 1905 209.5 No 0
MTCL1-201 ENSP00000382924
ENST00000400050
Q9Y4B5
Show all »
Show » Show » 1586 177.9 No 0