FNTA

GENERAL INFORMATION

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Gene name

FNTA

Gene description

Farnesyltransferase, CAAX box, alpha

Protein class

Enzymes
Predicted intracellular proteins

Predicted localization

Intracellular

Number of transcripts

5
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HUMAN PROTEIN ATLAS INFORMATION

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RNA tissue category

HPA:Expressed in all
GTEx:Expressed in all

Protein evidence

Evidence at protein level

Protein localization

Ubiquitous cytoplasmic and nuclear expression.

ANTIBODY RELIABILITY

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Data reliability
description

Pending RNA-based expert annotation.

Data reliability

Uncertain based on 2 antibodies.
HPA018830 , CAB010149
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RNA AND PROTEIN EXPRESSION SUMMARY

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RNA expression (FPKM) Protein expression (score)
Brain
Endocrine tissues
Bone marrow & immune system
Muscle tissues
Lung
Liver & gallbladder
Pancreas
Gastrointestinal tract
Kidney & urinary bladder
Male tissues
Female tissues
Adipose & soft tissue
Skin
Cerebral cortex

Lymph node

Liver

Colon

Kidney

Testis



PROTEIN EXPRESSION OVERVIEW

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Organ

Expression



RNA EXPRESSION OVERVIEW

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HPA dataset
RNA tissue category:  Expressed in all

Organ

Expression

GTEx dataset
RNA tissue category:  Expressed in all

Organ

Expression



GENE INFORMATION

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Gene name

FNTA (HGNC Symbol)

Synonyms

FPTA, PGGT1A, PTAR2

Description

Farnesyltransferase, CAAX box, alpha (HGNC Symbol)

Entrez gene summary

Prenyltransferases can attach either a farnesyl group or a geranylgeranyl group in thioether linkage to the cysteine residue of proteins with a C-terminal CAAX box. CAAX geranylgeranyltransferase and CAAX farnesyltransferase are heterodimers that share the same alpha subunit but have different beta subunits. This gene encodes the alpha subunit of these transferases. Alternative splicing results in multiple transcript variants. Related pseudogenes have been identified on chromosomes 11 and 13. [provided by RefSeq, May 2010]

Chromosome

8

Cytoband

p11.21

Chromosome location (bp)

43034194 - 43085788

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000168522 (version 78.38)

Entrez gene

2339

UniProt

P49354 (UniProt - Evidence at protein level)

neXtProt

NX_P49354

Antibodypedia

FNTA antibodies


PROTEIN BROWSER

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ENST00000302279
 
ENST00000525699
 
ENST00000529687
 
ENST00000531266
 
ENST00000533336
 
 
 
 


PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

FNTA-001 ENSP00000303423
ENST00000302279
P49354
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Show » Show » 379 44.4 No 0
FNTA-004 ENSP00000473479
ENST00000529687
B3KVN2
Show all »
Show » Show » 228 27.4 No 0
FNTA-007 ENSP00000434430
ENST00000533336
E9PQP6
Show all »
Show » Show » 249 30.1 No 0
FNTA-008 ENSP00000432411
ENST00000531266
H0YCW1
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Show » Show » 197 23 No 0
FNTA-009 ENSP00000436998
ENST00000525699
E9PPM9
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Show » Show » 60 7.5 No 0