ADAM29

GENERAL INFORMATION

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Gene name

ADAM29

Gene description

ADAM metallopeptidase domain 29

Protein class

Disease related genes
Enzymes
Potential drug targets
Predicted intracellular proteins
Predicted membrane proteins
Predicted secreted proteins

Predicted localization

Intracellular,Membrane,Secreted

Number of transcripts

9
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HUMAN PROTEIN ATLAS INFORMATION

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RNA tissue category

HPA:Tissue enriched (testis)
GTEx:Tissue enriched (testis)

Protein evidence

Evidence at protein level

Protein localization

RNA data suggests expression in testis. RNA-based expert annotation gave inconclusive results.

ANTIBODY RELIABILITY

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Data reliability
description

Antibody staining not consistent with RNA expression data. Presumed off target binding observed and disregarded.

Data reliability

Uncertain based on 1 antibody.
HPA014159
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RNA AND PROTEIN EXPRESSION SUMMARY

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RNA expression (FPKM) Protein expression (score)
Brain
N/A
Endocrine tissues
N/A
Bone marrow & immune system
N/A
Muscle tissues
N/A
Lung
N/A
Nasopharynx
N/A
N/A
Bronchus
N/A
N/A
Lung
N/A
Liver & gallbladder
N/A
Liver
N/A
Pancreas
N/A
Pancreas
N/A
Gastrointestinal tract
N/A
Kidney & urinary bladder
N/A
Male tissues
N/A
Testis
N/A
Epididymis
N/A
N/A
Prostate
N/A
Seminal vesicle
N/A
N/A
Female tissues
N/A
Breast
N/A
N/A
Vagina
N/A
N/A
Cervix, uterine
N/A
N/A
Ovary
N/A
Placenta
N/A
Adipose & soft tissue
N/A
Skin
N/A
Skin
N/A
Cerebral cortex

Lymph node

Liver

Colon

Kidney

Testis

Skin



PROTEIN EXPRESSION OVERVIEW

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RNA-based expert annotation could not be performed, due to inconclusive results. View immunohistochemistry primary data.


RNA EXPRESSION OVERVIEW

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HPA dataset
RNA tissue category:  Tissue enriched (testis)

Organ

Expression

GTEx dataset
RNA tissue category:  Tissue enriched (testis)

Organ

Expression



GENE INFORMATION

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Gene name

ADAM29 (HGNC Symbol)

Synonyms

CT73, svph1

Description

ADAM metallopeptidase domain 29 (HGNC Symbol)

Entrez gene summary

This gene encodes a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. The protein encoded by this gene is highly expressed in testis and may be involved in human spermatogenesis. Alternative splicing results in multiple transcript variants that encode the same protein. [provided by RefSeq, Jul 2008]

Chromosome

4

Cytoband

q34.1

Chromosome location (bp)

174829668 - 174978180

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000168594 (version 78.38)

Entrez gene

11086

UniProt

Q9UKF5 (UniProt - Evidence at protein level)

neXtProt

NX_Q9UKF5

Antibodypedia

ADAM29 antibodies


PROTEIN BROWSER

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ENST00000359240
 
ENST00000404450
 
ENST00000445694
 
ENST00000502305
 
ENST00000502940
 
ENST00000505141
 
ENST00000514159
 
ENST00000615367
 
ENST00000618444
 
 
 
 


PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

ADAM29-001 ENSP00000384229
ENST00000404450
Q9UKF5
Show all »
Show » Show » 820 92.8 Yes 1
ADAM29-002 ENSP00000423517
ENST00000514159
Q9UKF5
Show all »
Show » Show » 820 92.8 Yes 1
ADAM29-004 ENSP00000427370
ENST00000505141
Show » 14 1.6 No 0
ADAM29-005 ENSP00000427674
ENST00000502940
D6RHU0
Show all »
Show » Show » 90 10.1 Yes 0
ADAM29-006 ENSP00000422537
ENST00000502305
D6RBU0
Show all »
Show » 44 4.9 Yes 0
ADAM29-201 ENSP00000352177
ENST00000359240
Q9UKF5
Show all »
Show » Show » 820 92.8 Yes 1
ADAM29-202 ENSP00000414544
ENST00000445694
Q9UKF5
Show all »
Show » Show » 820 92.8 Yes 1
ADAM29-203 ENSP00000484862
ENST00000615367
Q9UKF5
Show all »
Show » Show » 820 92.8 Yes 1
ADAM29-204 ENSP00000478469
ENST00000618444
Q9UKF5
Show all »
Show » Show » 820 92.8 Yes 1