E2F6

GENERAL INFORMATION

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Gene name

E2F6

Gene description

E2F transcription factor 6

Protein class

Plasma proteins
Predicted intracellular proteins
Transcription factors

Predicted localization

Intracellular

Number of transcripts

4
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HUMAN PROTEIN ATLAS INFORMATION

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RNA tissue category

HPA:Expressed in all
GTEx:Expressed in all

Protein evidence

Evidence at protein level

ANTIBODY RELIABILITY

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Data reliability

Pending normal tissue annotation.
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RNA AND PROTEIN EXPRESSION SUMMARY

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RNA expression (FPKM) Protein expression (score)
Brain
N/A
Endocrine tissues
N/A
Bone marrow & immune system
N/A
Muscle tissues
N/A
Lung
N/A
Nasopharynx
N/A
N/A
Bronchus
N/A
N/A
Lung
N/A
Liver & gallbladder
N/A
Liver
N/A
Pancreas
N/A
Pancreas
N/A
Gastrointestinal tract
N/A
Kidney & urinary bladder
N/A
Male tissues
N/A
Testis
N/A
Epididymis
N/A
N/A
Prostate
N/A
Seminal vesicle
N/A
N/A
Female tissues
N/A
Breast
N/A
N/A
Vagina
N/A
N/A
Cervix, uterine
N/A
N/A
Ovary
N/A
Placenta
N/A
Adipose & soft tissue
N/A
Skin
N/A
Skin
N/A


PROTEIN EXPRESSION OVERVIEW

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Pending normal tissue annotation.


RNA EXPRESSION OVERVIEW

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HPA dataset
RNA tissue category:  Expressed in all

Organ

Expression

GTEx dataset
RNA tissue category:  Expressed in all

Organ

Expression



GENE INFORMATION

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Gene name

E2F6 (HGNC Symbol)

Synonyms

E2F-6

Description

E2F transcription factor 6 (HGNC Symbol)

Entrez gene summary

This gene encodes a member of a family of transcription factors that play a crucial role in the control of the cell cycle. The protein encoded by this gene lacks the transactivation and tumor suppressor protein association domains found in other family members, and contains a modular suppression domain that functions in the inhibition of transcription. It interacts in a complex with chromatin modifying factors. There are pseudogenes for this gene on chromosomes 22 and X. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2013]

Chromosome

2

Cytoband

p25.1

Chromosome location (bp)

11444375 - 11466177

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000169016 (version 78.38)

Entrez gene

1876

UniProt

O75461 (UniProt - Evidence at protein level)

neXtProt

NX_O75461

Antibodypedia

E2F6 antibodies


PROTEIN BROWSER

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ENST00000307236
 
ENST00000381525
 
ENST00000542100
 
ENST00000546212
 
 
 
 


PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

E2F6-001 ENSP00000370936
ENST00000381525
O75461
Show all »
Show » Show » 281 31.8 No 0
E2F6-201 ENSP00000302159
ENST00000307236
O75461
Show all »
Show » Show » 249 28.1 No 0
E2F6-202 ENSP00000446315
ENST00000542100
O75461
Show all »
Show » Show » 206 23 No 0
E2F6-203 ENSP00000438864
ENST00000546212
O75461
Show all »
Show » Show » 206 23 No 0