CA5B

GENERAL INFORMATION

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Gene name

CA5B

Gene description

Carbonic anhydrase VB, mitochondrial

Protein class

Enzymes
Mitochondrial proteins
Predicted intracellular proteins

Predicted localization

Intracellular

Number of transcripts

4
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HUMAN PROTEIN ATLAS INFORMATION

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RNA tissue category

HPA:Mixed
GTEx:Mixed

Protein evidence

Evidence at protein level

Protein localization

Mainly cytoplasmic expression in most tissues.

ANTIBODY RELIABILITY

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Data reliability
description

Pending RNA-based expert annotation.

Data reliability

Uncertain based on 1 antibody.
HPA012618
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RNA AND PROTEIN EXPRESSION SUMMARY

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RNA expression (FPKM) Protein expression (score)
Brain
Endocrine tissues
Bone marrow & immune system
Muscle tissues
Lung
Liver & gallbladder
Pancreas
Gastrointestinal tract
Kidney & urinary bladder
Male tissues
Female tissues
Adipose & soft tissue
Skin
Cerebral cortex

Lymph node

Skeletal muscle

Liver

Colon

Kidney

Testis



PROTEIN EXPRESSION OVERVIEW

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Organ

Expression



RNA EXPRESSION OVERVIEW

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HPA dataset
RNA tissue category:  Mixed

Organ

Expression

GTEx dataset
RNA tissue category:  Mixed

Organ

Expression



GENE INFORMATION

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Gene name

CA5B

Synonyms

Description

Carbonic anhydrase VB, mitochondrial (HGNC Symbol)

Entrez gene summary

Carbonic anhydrases (CAs) are a large family of zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide. They participate in a variety of biological processes, including respiration, calcification, acid-base balance, bone resorption, and the formation of aqueous humor, cerebrospinal fluid, saliva, and gastric acid. They show extensive diversity in tissue distribution and in their subcellular localization. CA VB is localized in the mitochondria and shows the highest sequence similarity to the other mitochondrial CA, CA VA. It has a wider tissue distribution than CA VA, which is restricted to the liver. The differences in tissue distribution suggest that the two mitochondrial carbonic anhydrases evolved to assume different physiologic roles. [provided by RefSeq, Jul 2008]

Chromosome

X

Cytoband

p22.2

Chromosome location (bp)

15688830 - 15787624

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000169239 (version 78.38)

Entrez gene

11238

UniProt

Q9Y2D0 (UniProt - Evidence at protein level)

neXtProt

NX_Q9Y2D0

Antibodypedia

CA5B antibodies


PROTEIN BROWSER

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ENST00000318636
 
ENST00000454127
 
ENST00000479740
 
ENST00000498004
 
 
 
 


PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

CA5B-005 ENSP00000314099
ENST00000318636
Q9Y2D0
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Show » Show » 317 36.4 No 0
CA5B-007 ENSP00000417553
ENST00000479740
C9JA11
Show all »
Show » Show » 136 15.8 No 0
CA5B-009 ENSP00000418622
ENST00000498004
C9IZP3
Show all »
Show » Show » 76 8.9 No 0
CA5B-201 ENSP00000417021
ENST00000454127
Q9Y2D0
Show all »
Show » Show » 317 36.4 No 0