HNRNPF

GENERAL INFORMATION

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Gene name

HNRNPF

Gene description

Heterogeneous nuclear ribonucleoprotein F

Protein class

Plasma proteins
Predicted intracellular proteins

Predicted localization

Intracellular

Number of transcripts

5
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HUMAN PROTEIN ATLAS INFORMATION

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RNA tissue category

HPA:Expressed in all
GTEx:Expressed in all

Protein evidence

Evidence at protein level

Protein localization

Ubiquitous nuclear expression.

ANTIBODY RELIABILITY

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Data reliability
description

Antibody staining mainly consistent with RNA expression data. Caution, targets protein from more than one gene.

Data reliability

Supportive based on 1 antibody.
HPA016884
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RNA AND PROTEIN EXPRESSION SUMMARY

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RNA expression (FPKM) Protein expression (score)
Brain
Endocrine tissues
Bone marrow & immune system
Muscle tissues
Lung
Liver & gallbladder
Pancreas
Gastrointestinal tract
Kidney & urinary bladder
Male tissues
Female tissues
Adipose & soft tissue
Skin
Cerebral cortex

Lymph node

Liver

Colon

Kidney

Testis



PROTEIN EXPRESSION OVERVIEW

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Organ

Expression



RNA EXPRESSION OVERVIEW

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HPA dataset
RNA tissue category:  Expressed in all

Organ

Expression

GTEx dataset
RNA tissue category:  Expressed in all

Organ

Expression



GENE INFORMATION

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Gene name

HNRNPF (HGNC Symbol)

Synonyms

HNRPF

Description

Heterogeneous nuclear ribonucleoprotein F (HGNC Symbol)

Entrez gene summary

This gene belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA binding proteins that complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and regulate alternative splicing, polyadenylation, and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene has three repeats of quasi-RRM domains that bind to RNAs which have guanosine-rich sequences. This protein is very similar to the family member hnRPH. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Jul 2008]

Chromosome

10

Cytoband

q11.21

Chromosome location (bp)

43385617 - 43409166

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000169813 (version 78.38)

Entrez gene

3185

UniProt

P52597 (UniProt - Evidence at protein level)

neXtProt

NX_P52597

Antibodypedia

HNRNPF antibodies


PROTEIN BROWSER

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ENST00000337970
 
ENST00000356053
 
ENST00000357065
 
ENST00000443950
 
ENST00000544000
 
 
 
 


PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

HNRNPF-001 ENSP00000349573
ENST00000357065
P52597
Show all »
Show » Show » 415 45.7 No 0
HNRNPF-004 ENSP00000338477
ENST00000337970
P52597
Show all »
Show » Show » 415 45.7 No 0
HNRNPF-005 ENSP00000348345
ENST00000356053
P52597
Show all »
Show » Show » 415 45.7 No 0
HNRNPF-201 ENSP00000400433
ENST00000443950
P52597
Show all »
Show » Show » 415 45.7 No 0
HNRNPF-202 ENSP00000438061
ENST00000544000
P52597
Show all »
Show » Show » 415 45.7 No 0