The primary data page shows the detailed antibody staining in 76 different cell types for each analyzed antibody. In addition, for each cell type, a knowledge-based annotated protein expression score based on all analyzed antibodies is displayed furthest to the right. The images and annotations can be accessed by clicking on the tissue name or score bar. More information can be found in Assays & Annotation.
The tissues and cell types can be ordered by organ, cell type or alphabetically. If ordered by organ, the tissues are presented in groups according to functional features. If ordered by cell type, the cells are presented in groups related to origin.
This score describes the level of antibody staining observed in the annotated cell types as not detected (n), low (l), medium (m) or high (h). It is based on the staining intensity and fraction of stained cells. The images and annotations can be accessed by clicking on the tissue name or score bar. More information can be found in Assays & Annotation.
This score describes a knowledge-based best estimate of the protein expression in the annotated cell types as not detected (n), low (l), medium (m) or high (h). It is a result of stringent evaluation of immunohistochemical staining pattern, RNA data from internal and external sources and available protein/gene characterization data. More information can be found in Assays & Annotation.
Summarizing texts describe the staining pattern for each antibody based on staining intensity, fraction of stained cells and subcellular localization. More information can be found in Assays & Annotation.
Cells in thymus displayed strong cytoplasmic positivity. Renal tubules, thyroid, stomach and a subset of cells in the adrenal, non-germinal center cells, prostate and skin showed moderate cytoplasmic staining. A subset of cells in fallopian tube, respiratory epithelium of nasopharynx, intestine, gallbladder and urothelial cells displayed weak to moderate membranous positivity. Remaining normal tissues were negative.
Gastrointestinal tract and renal tubules displayed strong granular cytoplasmic positivity. A subset of lymphoid tissues showed moderate to strong immunoreactivity. The adrenal, lung macrophages, gallbladder, parathyroid, Leydig cells and adipocytes showed moderate positivity. Inflammatory cells were distinctly stained. Remaining normal tissues were negative.