SLCO2A1

GENERAL INFORMATION

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Gene name

SLCO2A1

Gene description

Solute carrier organic anion transporter family, member 2A1

Protein class

Disease related genes
Potential drug targets
Predicted membrane proteins
Transporters

Predicted localization

Membrane

Number of transcripts

2
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HUMAN PROTEIN ATLAS INFORMATION

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RNA tissue category

HPA:Mixed
GTEx:Tissue enhanced (lung)

Protein evidence

Evidence at protein level

Protein localization

Strong cytoplasmic and membranous positivity was observed in endothelial cells, glandular cells of seminal vesicle and glomeruli of kidney. Neuronal cells displayed nuclear positivity. Remaining normal tissues were generally negative.

ANTIBODY RELIABILITY

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Data reliability
description

Pending RNA-based expert annotation.

Data reliability

Uncertain based on 1 antibody.
HPA013742
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RNA AND PROTEIN EXPRESSION SUMMARY

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RNA expression (FPKM) Protein expression (score)
Brain
Endocrine tissues
Bone marrow & immune system
Muscle tissues
Lung
Liver & gallbladder
Pancreas
Gastrointestinal tract
Kidney & urinary bladder
Male tissues
Female tissues
Adipose & soft tissue
Skin
Cerebral cortex

Lymph node

Liver

Colon

Kidney

Testis

Skin



PROTEIN EXPRESSION OVERVIEW

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Organ

Expression



RNA EXPRESSION OVERVIEW

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HPA dataset
RNA tissue category:  Mixed

Organ

Expression

GTEx dataset
RNA tissue category:  Tissue enhanced (lung)

Organ

Expression



GENE INFORMATION

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Gene name

SLCO2A1 (HGNC Symbol)

Synonyms

MATR1, OATP2A1, PGT, SLC21A2

Description

Solute carrier organic anion transporter family, member 2A1 (HGNC Symbol)

Entrez gene summary

This gene encodes a prostaglandin transporter that is a member of the 12-membrane-spanning superfamily of transporters. The encoded protein may be involved in mediating the uptake and clearance of prostaglandins in numerous tissues. [provided by RefSeq, Dec 2011]

Chromosome

3

Cytoband

Chromosome location (bp)

133932696 - 134052184

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000174640 (version 78.38)

Entrez gene

6578

UniProt

Q92959 (UniProt - Evidence at protein level)

neXtProt

NX_Q92959

Antibodypedia

SLCO2A1 antibodies


PROTEIN BROWSER

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ENST00000310926
 
ENST00000493729
 
 
 
 


PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

SLCO2A1-001 ENSP00000311291
ENST00000310926
Q92959
Show all »
Show » Show » 643 70 No >9
SLCO2A1-004 ENSP00000418893
ENST00000493729
E7EU40
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Show » Show » 567 61.7 No >9