PABPC5

GENERAL INFORMATION

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Gene name

PABPC5

Gene description

Poly(A) binding protein, cytoplasmic 5

Protein class

Predicted intracellular proteins

Predicted localization

Intracellular

Number of transcripts

2
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HUMAN PROTEIN ATLAS INFORMATION

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RNA tissue category

HPA:Tissue enhanced (ovary)
GTEx:Mixed

Protein evidence

Evidence at protein level

Protein localization

Cytoplasmic expression in most tissues.

ANTIBODY RELIABILITY

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Data reliability
description

Pending RNA-based expert annotation.

Data reliability

Supportive based on 2 antibodies.
HPA000164 , HPA000165
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RNA AND PROTEIN EXPRESSION SUMMARY

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RNA expression (FPKM) Protein expression (score)
Brain
Endocrine tissues
Bone marrow & immune system
Muscle tissues
Lung
Liver & gallbladder
Pancreas
Gastrointestinal tract
Kidney & urinary bladder
Male tissues
Female tissues
Adipose & soft tissue
Skin
Cerebral cortex

Lymph node

Liver

Colon

Kidney

Testis



PROTEIN EXPRESSION OVERVIEW

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Organ

Expression



RNA EXPRESSION OVERVIEW

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HPA dataset
RNA tissue category:  Tissue enhanced (ovary)

Organ

Expression

GTEx dataset
RNA tissue category:  Mixed

Organ

Expression



GENE INFORMATION

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Gene name

PABPC5 (HGNC Symbol)

Synonyms

PABP5

Description

Poly(A) binding protein, cytoplasmic 5 (HGNC Symbol)

Entrez gene summary

This gene encodes a protein that binds to the polyA tail found at the 3' end of most eukaryotic mRNAs. It is thought to play a role in the regulation of mRNA metabolic processes in the cytoplasm. This gene is located in a gene-poor region within the X-specific 13d-sY43 subinterval of the chromosome Xq21.3/Yp11.2 homology block. It is located close to translocation breakpoints associated with premature ovarian failure, and is therefore a potential candidate gene for this disorder. [provided by RefSeq, May 2010]

Chromosome

X

Cytoband

q21.31

Chromosome location (bp)

91434595 - 91438584

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000174740 (version 78.38)

Entrez gene

140886

UniProt

Q96DU9 (UniProt - Evidence at transcript level)

neXtProt

NX_Q96DU9

Antibodypedia

PABPC5 antibodies


PROTEIN BROWSER

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ENST00000312600
 
ENST00000373105
 
 
 
 


PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

PABPC5-001 ENSP00000308012
ENST00000312600
Q96DU9
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Show » Show » 382 43.3 No 0
PABPC5-002 ENSP00000362197
ENST00000373105
Q5JQF3
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Show » Show » 218 24.8 No 0