CNIH2

GENERAL INFORMATION

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Gene name

CNIH2

Gene description

Cornichon family AMPA receptor auxiliary protein 2

Protein class

Predicted membrane proteins

Predicted localization

Membrane

Number of transcripts

2
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HUMAN PROTEIN ATLAS INFORMATION

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RNA tissue category

HPA:Tissue enriched (cerebral cortex)
GTEx:Tissue enhanced (cerebral cortex, hippocampus)

Protein evidence

Evidence at protein level

ANTIBODY RELIABILITY

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Data reliability

Pending normal tissue annotation.
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RNA AND PROTEIN EXPRESSION SUMMARY

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RNA expression (FPKM) Protein expression (score)
Brain
N/A
Endocrine tissues
N/A
Bone marrow & immune system
N/A
Muscle tissues
N/A
Lung
N/A
Nasopharynx
N/A
N/A
Bronchus
N/A
N/A
Lung
N/A
Liver & gallbladder
N/A
Liver
N/A
Pancreas
N/A
Pancreas
N/A
Gastrointestinal tract
N/A
Kidney & urinary bladder
N/A
Male tissues
N/A
Testis
N/A
Epididymis
N/A
N/A
Prostate
N/A
Seminal vesicle
N/A
N/A
Female tissues
N/A
Breast
N/A
N/A
Vagina
N/A
N/A
Cervix, uterine
N/A
N/A
Ovary
N/A
Placenta
N/A
Adipose & soft tissue
N/A
Skin
N/A
Skin
N/A


PROTEIN EXPRESSION OVERVIEW

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Pending normal tissue annotation.


RNA EXPRESSION OVERVIEW

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HPA dataset
RNA tissue category:  Tissue enriched (cerebral cortex)

Organ

Expression

GTEx dataset
RNA tissue category:  Tissue enhanced (cerebral cortex, hippocampus)

Organ

Expression



GENE INFORMATION

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Gene name

CNIH2 (HGNC Symbol)

Synonyms

CNIH-2, Cnil, MGC50896

Description

Cornichon family AMPA receptor auxiliary protein 2 (HGNC Symbol)

Entrez gene summary

The protein encoded by this gene is an auxiliary subunit of the ionotropic glutamate receptor of the AMPA subtype. AMPA receptors mediate fast synaptic neurotransmission in the central nervous system. This protein has been reported to interact with the Type I AMPA receptor regulatory protein isoform gamma-8 to control assembly of hippocampal AMPA receptor complexes, thereby modulating receptor gating and pharmacology. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2012]

Chromosome

11

Cytoband

q13.2

Chromosome location (bp)

66278190 - 66285301

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000174871 (version 78.38)

Entrez gene

254263

UniProt

Q6PI25 (UniProt - Evidence at protein level)

neXtProt

NX_Q6PI25

Antibodypedia

CNIH2 antibodies


PROTEIN BROWSER

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ENST00000311445
 
ENST00000528852
 
 
 
 


PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

CNIH2-001 ENSP00000310003
ENST00000311445
Q6PI25
Show all »
Show » Show » 160 18.9 No 3
CNIH2-002 ENSP00000432177
ENST00000528852
E9PS15
Show all »
Show » Show » 152 18.1 No 3