EPS8L2

GENERAL INFORMATION

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Gene name

EPS8L2

Gene description

EPS8-like 2

Protein class

Predicted intracellular proteins

Predicted localization

Intracellular

Number of transcripts

11
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HUMAN PROTEIN ATLAS INFORMATION

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RNA tissue category

HPA:Mixed
GTEx:Mixed

Protein evidence

Evidence at protein level

Protein localization

Most of the normal tissues displayed moderate to strong cytoplasmic positivity. Additional membranous staining was observed in gastrointestinal tract, renal tubules, exocrine pancreas and uterine glands. Testis, parathyroid,fibroblasts,endothelia,adipocytes and lymphoid tissues were generally negative.

ANTIBODY RELIABILITY

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Data reliability
description

Pending RNA-based expert annotation.

Data reliability

Uncertain based on 1 antibody.
HPA041143
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RNA AND PROTEIN EXPRESSION SUMMARY

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RNA expression (FPKM) Protein expression (score)
Brain
Endocrine tissues
Bone marrow & immune system
Muscle tissues
Lung
Liver & gallbladder
Pancreas
Gastrointestinal tract
Kidney & urinary bladder
Male tissues
Female tissues
Adipose & soft tissue
Skin
Cerebral cortex

Lymph node

Liver

Colon

Kidney

Testis

Placenta



PROTEIN EXPRESSION OVERVIEW

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Organ

Expression



RNA EXPRESSION OVERVIEW

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HPA dataset
RNA tissue category:  Mixed

Organ

Expression

GTEx dataset
RNA tissue category:  Mixed

Organ

Expression



GENE INFORMATION

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Gene name

EPS8L2 (HGNC Symbol)

Synonyms

FLJ21935, FLJ22171, MGC3088

Description

EPS8-like 2 (HGNC Symbol)

Entrez gene summary

This gene encodes a member of the EPS8 gene family. The encoded protein, like other members of the family, is thought to link growth factor stimulation to actin organization, generating functional redundancy in the pathways that regulate actin cytoskeletal remodeling. [provided by RefSeq, Dec 2008]

Chromosome

11

Cytoband

p15.5

Chromosome location (bp)

694438 - 727727

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000177106 (version 78.38)

Entrez gene

64787

UniProt

Q9H6S3 (UniProt - Evidence at protein level)

neXtProt

NX_Q9H6S3

Antibodypedia

EPS8L2 antibodies


PROTEIN BROWSER

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ENST00000318562
 
ENST00000524763
 
ENST00000526198
 
ENST00000527199
 
ENST00000530636
 
ENST00000531348
 
ENST00000533256
 
ENST00000533500
 
ENST00000534755
 
ENST00000610855
 
ENST00000614442
 
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PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

EPS8L2-001 ENSP00000320828
ENST00000318562
Q9H6S3
Show all »
Show » Show » 715 80.6 No 0
EPS8L2-002 ENSP00000436035
ENST00000530636
Q9H6S3
Show all »
Show » Show » 715 80.6 No 0
EPS8L2-003 ENSP00000435585
ENST00000533256
Q9H6S3
Show all »
Show » Show » 715 80.6 No 0
EPS8L2-006 ENSP00000436230
ENST00000526198
Q9H6S3
Show all »
Show » Show » 731 82.3 No 0
EPS8L2-008 ENSP00000435128
ENST00000524763
E9PLH1
Show all »
Show » Show » 105 11.7 No 0
EPS8L2-009 ENSP00000437085
ENST00000527199
E9PNY4
Show all »
Show » 25 2.3 No 0
EPS8L2-016 ENSP00000433223
ENST00000533500
E9PLN2
Show all »
Show » Show » 83 9 No 0
EPS8L2-026 ENSP00000432765
ENST00000531348
E9PNT0
Show all »
Show » Show » 95 10.5 No 0
EPS8L2-027 ENSP00000432923
ENST00000534755
E9PN68
Show all »
Show » Show » 79 8.6 No 0
EPS8L2-201 ENSP00000480704
ENST00000610855
Show » Show » 232 25.4 No 0
EPS8L2-202 ENSP00000480201
ENST00000614442
Q9H6S3
Show all »
Show » Show » 731 82.3 No 0