SLC25A21

GENERAL INFORMATION

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Gene name

SLC25A21

Gene description

Solute carrier family 25 (mitochondrial oxoadipate carrier), member 21

Protein class

Mitochondrial proteins
Predicted intracellular proteins
Transporters

Predicted localization

Intracellular

Number of transcripts

3
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HUMAN PROTEIN ATLAS INFORMATION

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RNA tissue category

HPA:Tissue enhanced (bone marrow, testis)
GTEx:Tissue enhanced (testis)

Protein evidence

Evidence at protein level

Protein localization

Basal cells in prostate, seminal vesicle, epididymis and urothelium showed moderate to strong cytoplasmic positivity. Cells in CNS, lymphoid tissues and glandular cells in gastrointestinal tract were generally weakly stained or negative.

ANTIBODY RELIABILITY

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Data reliability
description

Pending RNA-based expert annotation.

Data reliability

Uncertain based on 1 antibody.
HPA000662
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RNA AND PROTEIN EXPRESSION SUMMARY

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RNA expression (FPKM) Protein expression (score)
Brain
Endocrine tissues
Bone marrow & immune system
Muscle tissues
Lung
Liver & gallbladder
Pancreas
Gastrointestinal tract
Kidney & urinary bladder
Male tissues
Female tissues
Adipose & soft tissue
Skin
Cerebral cortex

Lymph node

Liver

Colon

Kidney

Testis



PROTEIN EXPRESSION OVERVIEW

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Organ

Expression



RNA EXPRESSION OVERVIEW

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HPA dataset
RNA tissue category:  Tissue enhanced (bone marrow, testis)

Organ

Expression

GTEx dataset
RNA tissue category:  Tissue enhanced (testis)

Organ

Expression



GENE INFORMATION

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Gene name

SLC25A21 (HGNC Symbol)

Synonyms

ODC, ODC1

Description

Solute carrier family 25 (mitochondrial oxoadipate carrier), member 21 (HGNC Symbol)

Entrez gene summary

SLC25A21 is a homolog of the S. cerevisiae ODC proteins, mitochondrial carriers that transport C5-C7 oxodicarboxylates across inner mitochondrial membranes. One of the species transported by ODC is 2-oxoadipate, a common intermediate in the catabolism of lysine, tryptophan, and hydroxylysine in mammals. Within mitochondria, 2-oxoadipate is converted into acetyl-CoA.[supplied by OMIM, Apr 2004]

Chromosome

14

Cytoband

q13.3

Chromosome location (bp)

36677921 - 37172866

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000183032 (version 78.38)

Entrez gene

89874

UniProt

Q9BQT8 (UniProt - Evidence at protein level)

neXtProt

NX_Q9BQT8

Antibodypedia

SLC25A21 antibodies


PROTEIN BROWSER

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ENST00000331299
 
ENST00000555449
 
ENST00000622765
 
 
 
 


PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

SLC25A21-001 ENSP00000329452
ENST00000331299
Q9BQT8
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Show » Show » 299 33.3 No 0
SLC25A21-004 ENSP00000451873
ENST00000555449
Q9BQT8
Show all »
Show » Show » 298 33.1 No 0
SLC25A21-201 ENSP00000481445
ENST00000622765
Show » 234 26.1 No 0