MAGEA11

GENERAL INFORMATION

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Gene name

MAGEA11

Gene description

Melanoma antigen family A, 11

Protein class

Predicted intracellular proteins

Predicted localization

Intracellular

Number of transcripts

3
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HUMAN PROTEIN ATLAS INFORMATION

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RNA tissue category

HPA:Tissue enriched (testis)
GTEx:Tissue enriched (testis)

Protein evidence

Evidence at protein level

Protein localization

Nuclear expression in cells in seminiferous ducts.

ANTIBODY RELIABILITY

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Data reliability
description

Antibody staining mainly not consistent with RNA expression data. Cytoplasmic binding observed and disregarded. In retesting.

Data reliability

Uncertain based on 1 antibody.
HPA045377
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RNA AND PROTEIN EXPRESSION SUMMARY

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RNA expression (FPKM) Protein expression (score)
Brain
Endocrine tissues
Bone marrow & immune system
Muscle tissues
Lung
Liver & gallbladder
Pancreas
Gastrointestinal tract
Kidney & urinary bladder
Male tissues
Female tissues
Adipose & soft tissue
Skin
Cerebral cortex

Lymph node

Liver

Colon

Kidney

Testis



PROTEIN EXPRESSION OVERVIEW

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Organ

Expression



RNA EXPRESSION OVERVIEW

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HPA dataset
RNA tissue category:  Tissue enriched (testis)

Organ

Expression

GTEx dataset
RNA tissue category:  Tissue enriched (testis)

Organ

Expression



GENE INFORMATION

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Gene name

MAGEA11 (HGNC Symbol)

Synonyms

CT1.11, MAGE-11, MAGE11, MAGEA-11, MGC10511

Description

Melanoma antigen family A, 11 (HGNC Symbol)

Entrez gene summary

This gene is a member of the MAGEA gene family. The members of this family encode proteins with 50 to 80% sequence identity to each other. The promoters and first exons of the MAGEA genes show considerable variability, suggesting that the existence of this gene family enables the same function to be expressed under different transcriptional controls. The MAGEA genes are clustered at chromosomal location Xq28. They have been implicated in some hereditary disorders, such as dyskeratosis congenita. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

Chromosome

X

Cytoband

q28

Chromosome location (bp)

149688228 - 149717266

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000185247 (version 78.38)

Entrez gene

4110

UniProt

P43364 (UniProt - Evidence at protein level)

neXtProt

NX_P43364

Antibodypedia

MAGEA11 antibodies


PROTEIN BROWSER

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ENST00000333104
 
ENST00000355220
 
ENST00000412632
 
 
 
 


PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

MAGEA11-001 ENSP00000347358
ENST00000355220
P43364
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Show » Show » 429 48.1 No 0
MAGEA11-002 ENSP00000391496
ENST00000412632
C9J2X2
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Show » Show » 295 32.9 No 0
MAGEA11-201 ENSP00000328177
ENST00000333104
G5E962
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Show » Show » 400 44.9 No 0