UBE2H

GENERAL INFORMATION

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Gene name

UBE2H

Gene description

Ubiquitin-conjugating enzyme E2H

Protein class

Enzymes
Predicted intracellular proteins

Predicted localization

Intracellular

Number of transcripts

5
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HUMAN PROTEIN ATLAS INFORMATION

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RNA tissue category

HPA:Expressed in all
GTEx:Expressed in all

Protein evidence

Evidence at protein level

Protein localization

Moderate to strong cytoplasmic staining was observed in most normal tissues.

ANTIBODY RELIABILITY

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Data reliability
description

Pending RNA-based expert annotation.

Data reliability

Uncertain based on 1 antibody.
HPA003302
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RNA AND PROTEIN EXPRESSION SUMMARY

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RNA expression (FPKM) Protein expression (score)
Brain
Endocrine tissues
Bone marrow & immune system
Muscle tissues
Lung
Nasopharynx
N/A
N/A
Bronchus
N/A
Liver & gallbladder
Pancreas
Gastrointestinal tract
Kidney & urinary bladder
Male tissues
Female tissues
Adipose & soft tissue
Skin
Cerebral cortex

Lymph node

Liver

Rectum

Kidney

Testis



PROTEIN EXPRESSION OVERVIEW

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Organ

Expression



RNA EXPRESSION OVERVIEW

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HPA dataset
RNA tissue category:  Expressed in all

Organ

Expression

GTEx dataset
RNA tissue category:  Expressed in all

Organ

Expression



GENE INFORMATION

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Gene name

UBE2H (HGNC Symbol)

Synonyms

GID3, UBC8, UBCH

Description

Ubiquitin-conjugating enzyme E2H (HGNC Symbol)

Entrez gene summary

The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. The encoded protein sequence is 100% identical to the mouse homolog and 98% identical to the frog and zebrafish homologs. Three alternatively spliced transcript variants have been found for this gene and they encode distinct isoforms. [provided by RefSeq, Feb 2011]

Chromosome

7

Cytoband

q32.2

Chromosome location (bp)

129830732 - 129952949

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000186591 (version 78.38)

Entrez gene

7328

UniProt

P62256 (UniProt - Evidence at protein level)

neXtProt

NX_P62256

Antibodypedia

UBE2H antibodies


PROTEIN BROWSER

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ENST00000355621
 
ENST00000472396
 
ENST00000473814
 
ENST00000490974
 
ENST00000496698
 
 
 
 


PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

UBE2H-001 ENSP00000347836
ENST00000355621
P62256
Show all »
Show » Show » 183 20.7 No 0
UBE2H-003 ENSP00000419750
ENST00000490974
C9JZG9
Show all »
Show » Show » 103 11.5 No 0
UBE2H-004 ENSP00000419689
ENST00000472396
C9JZY6
Show all »
Show » Show » 123 13.8 No 0
UBE2H-006 ENSP00000419097
ENST00000473814
P62256
Show all »
Show » Show » 152 17.2 No 0
UBE2H-009 ENSP00000417681
ENST00000496698
C9J8Q9
Show all »
Show » Show » 149 16.9 No 0