AGMO

GENERAL INFORMATION

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Gene name

AGMO

Gene description

Alkylglycerol monooxygenase

Protein class

Enzymes
Predicted intracellular proteins
Predicted membrane proteins

Predicted localization

Intracellular,Membrane

Number of transcripts

3
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HUMAN PROTEIN ATLAS INFORMATION

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RNA tissue category

HPA:Tissue enhanced (liver)
GTEx:Tissue enhanced (liver)

Protein evidence

Evidence at protein level

Protein localization

Moderate to strong cytoplasmic and nucelar positivity was observed in most normal tissues. The liver and glial cells were weakly stained or negative.

ANTIBODY RELIABILITY

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Data reliability
description

Pending RNA-based expert annotation.

Data reliability

Uncertain based on 1 antibody.
HPA040332
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RNA AND PROTEIN EXPRESSION SUMMARY

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RNA expression (FPKM) Protein expression (score)
Brain
Endocrine tissues
Bone marrow & immune system
Muscle tissues
Lung
Liver & gallbladder
Pancreas
Gastrointestinal tract
Kidney & urinary bladder
Male tissues
Female tissues
Adipose & soft tissue
Skin
Cerebral cortex

Lymph node

Liver

Colon

Kidney

Testis



PROTEIN EXPRESSION OVERVIEW

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Organ

Expression



RNA EXPRESSION OVERVIEW

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HPA dataset
RNA tissue category:  Tissue enhanced (liver)

Organ

Expression

GTEx dataset
RNA tissue category:  Tissue enhanced (liver)

Organ

Expression



GENE INFORMATION

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Gene name

AGMO (HGNC Symbol)

Synonyms

FLJ16237, TMEM195

Description

Alkylglycerol monooxygenase (HGNC Symbol)

Entrez gene summary

The protein encoded by this gene is a tetrahydrobiopterin- and iron-dependent enzyme that cleaves the ether bond of alkylglycerols. Sequence comparisons distinguish this protein as forming a third, distinct class of tetrahydrobiopterin-dependent enzymes. Variations in this gene have been associated with decreased glucose-stimulated insulin response, type 2 diabetes, and susceptibility to intracranial aneurysms. [provided by RefSeq, Aug 2012]

Chromosome

7

Cytoband

p21.2

Chromosome location (bp)

15200318 - 15562015

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000187546 (version 78.38)

Entrez gene

392636

UniProt

Q6ZNB7 (UniProt - Evidence at protein level)

neXtProt

NX_Q6ZNB7

Antibodypedia

AGMO antibodies


PROTEIN BROWSER

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ENST00000342526
 
ENST00000407277
 
ENST00000418075
 
 
 
 


PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

AGMO-001 ENSP00000341662
ENST00000342526
Q6ZNB7
Show all »
Show » Show » 445 51.5 No 8
AGMO-003 ENSP00000394412
ENST00000418075
H7C0E0
Show all »
Show » 74 8.3 No 2
AGMO-004 ENSP00000385742
ENST00000407277
Show » 87 9.6 No 0