SLC18A3

GENERAL INFORMATION

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Gene name

SLC18A3

Gene description

Solute carrier family 18 (vesicular acetylcholine transporter), member 3

Protein class

Predicted membrane proteins
Transporters

Predicted localization

Membrane

Number of transcripts

1
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HUMAN PROTEIN ATLAS INFORMATION

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RNA tissue category

HPA:Not detected
GTEx:Tissue enhanced (colon)

Protein evidence

Evidence at protein level

Protein localization

RNA-based expert annotation gave inconclusive results.

ANTIBODY RELIABILITY

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Data reliability
description

No RNA expression data detected and pending external verification. Presumed off target binding observed and disregarded.

Data reliability

Uncertain based on 1 antibody.
CAB037102
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RNA AND PROTEIN EXPRESSION SUMMARY

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RNA expression (FPKM) Protein expression (score)
Brain
N/A
Endocrine tissues
N/A
Bone marrow & immune system
N/A
Muscle tissues
N/A
Lung
N/A
Nasopharynx
N/A
N/A
Bronchus
N/A
N/A
Lung
N/A
Liver & gallbladder
N/A
Liver
N/A
Pancreas
N/A
Pancreas
N/A
Gastrointestinal tract
N/A
Kidney & urinary bladder
N/A
Male tissues
N/A
Testis
N/A
Epididymis
N/A
N/A
Prostate
N/A
Seminal vesicle
N/A
N/A
Female tissues
N/A
Breast
N/A
N/A
Vagina
N/A
N/A
Cervix, uterine
N/A
N/A
Ovary
N/A
Placenta
N/A
Adipose & soft tissue
N/A
Skin
N/A
Skin
N/A
Cerebral cortex

Lymph node

Tonsil

Liver

Colon

Kidney

Testis



PROTEIN EXPRESSION OVERVIEW

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RNA-based expert annotation could not be performed, due to inconclusive results. View immunohistochemistry primary data.


RNA EXPRESSION OVERVIEW

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HPA dataset
RNA tissue category:  Not detected

Organ

Expression

GTEx dataset
RNA tissue category:  Tissue enhanced (colon)

Organ

Expression



GENE INFORMATION

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Gene name

SLC18A3 (HGNC Symbol)

Synonyms

VACHT

Description

Solute carrier family 18 (vesicular acetylcholine transporter), member 3 (HGNC Symbol)

Entrez gene summary

This gene is a member of the vesicular amine transporter family. The encoded transmembrane protein transports acetylcholine into secretory vesicles for release into the extracellular space. Acetylcholine transport utilizes a proton gradient established by a vacuolar ATPase. This gene is located within the first intron of the choline acetyltransferase gene. [provided by RefSeq, Jul 2008]

Chromosome

10

Cytoband

q11.23

Chromosome location (bp)

49610301 - 49612720

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000187714 (version 78.38)

Entrez gene

6572

UniProt

Q16572 (UniProt - Evidence at protein level)

neXtProt

NX_Q16572

Antibodypedia

SLC18A3 antibodies


PROTEIN BROWSER

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ENST00000374115
 
 
 
 


PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

SLC18A3-001 ENSP00000363229
ENST00000374115
Q16572
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