SLC4A5

GENERAL INFORMATION

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Gene name

SLC4A5

Gene description

Solute carrier family 4 (sodium bicarbonate cotransporter), member 5

Protein class

Cancer-related genes
Predicted intracellular proteins
Predicted membrane proteins

Predicted localization

Intracellular,Membrane

Number of transcripts

10
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HUMAN PROTEIN ATLAS INFORMATION

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RNA tissue category

HPA:Group enriched (testis, thyroid gland)
GTEx:Group enriched (testis, thyroid gland)

Protein evidence

Evidence at protein level

ANTIBODY RELIABILITY

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Data reliability

Pending normal tissue annotation.
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RNA AND PROTEIN EXPRESSION SUMMARY

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RNA expression (FPKM) Protein expression (score)
Brain
N/A
Endocrine tissues
N/A
Bone marrow & immune system
N/A
Muscle tissues
N/A
Lung
N/A
Nasopharynx
N/A
N/A
Bronchus
N/A
N/A
Lung
N/A
Liver & gallbladder
N/A
Liver
N/A
Pancreas
N/A
Pancreas
N/A
Gastrointestinal tract
N/A
Kidney & urinary bladder
N/A
Male tissues
N/A
Testis
N/A
Epididymis
N/A
N/A
Prostate
N/A
Seminal vesicle
N/A
N/A
Female tissues
N/A
Breast
N/A
N/A
Vagina
N/A
N/A
Cervix, uterine
N/A
N/A
Ovary
N/A
Placenta
N/A
Adipose & soft tissue
N/A
Skin
N/A
Skin
N/A


PROTEIN EXPRESSION OVERVIEW

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Pending normal tissue annotation.


RNA EXPRESSION OVERVIEW

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HPA dataset
RNA tissue category:  Group enriched (testis, thyroid gland)

Organ

Expression

GTEx dataset
RNA tissue category:  Group enriched (testis, thyroid gland)

Organ

Expression



GENE INFORMATION

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Gene name

SLC4A5 (HGNC Symbol)

Synonyms

NBC4

Description

Solute carrier family 4 (sodium bicarbonate cotransporter), member 5 (HGNC Symbol)

Entrez gene summary

This gene encodes a member of the sodium bicarbonate cotransporter (NBC) family, part of the bicarbonate transporter superfamily. Sodium bicarbonate cotransporters are involved in intracellular pH regulation and electroneural or electrogenic sodium bicarbonate transport. This protein is thought to be an integral membrane protein. Multiple transcript variants encoding different isoforms have been found for this gene, but the biological validity of some variants has not been determined. [provided by RefSeq, Jul 2008]

Chromosome

2

Cytoband

p13.1

Chromosome location (bp)

74216242 - 74343414

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000188687 (version 78.38)

Entrez gene

57835

UniProt

Q9BY07 (UniProt - Evidence at transcript level)

neXtProt

NX_Q9BY07

Antibodypedia

SLC4A5 antibodies


PROTEIN BROWSER

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ENST00000346834
 
ENST00000358683
 
ENST00000377632
 
ENST00000377634
 
ENST00000394019
 
ENST00000423644
 
ENST00000425249
 
ENST00000432728
 
ENST00000436454
 
ENST00000444570
 
 
 
 


PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

SLC4A5-001 ENSP00000366861
ENST00000377634
Q9BY07
Show all »
Show » Show » 1137 126.3 No >9
SLC4A5-002 ENSP00000377587
ENST00000394019
Q9BY07
Show all »
Show » Show » 1121 124.6 No >9
SLC4A5-003 ENSP00000366859
ENST00000377632
Q9BY07
Show all »
Show » Show » 1040 115.2 No 9
SLC4A5-006 ENSP00000405678
ENST00000425249
E7EQT3
Show all »
Show » Show » 964 105.7 No 6
SLC4A5-007 ENSP00000351513
ENST00000358683
Q9BY07
Show all »
Show » Show » 1019 113.4 No >9
SLC4A5-008 ENSP00000399319
ENST00000436454
C9JW32
Show all »
Show » Show » 129 14.5 No 0
SLC4A5-009 ENSP00000407550
ENST00000444570
C9JU12
Show all »
Show » Show » 145 16.4 No 0
SLC4A5-012 ENSP00000414162
ENST00000432728
C9JNL6
Show all »
Show » Show » 122 14.2 No 0
SLC4A5-201 ENSP00000251768
ENST00000346834
Q9BY07
Show all »
Show » Show » 1137 126.3 No >9
SLC4A5-202 ENSP00000395804
ENST00000423644
Q9BY07
Show all »
Show » Show » 1121 124.6 No >9