GRAPL

GENERAL INFORMATION

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Gene name

GRAPL

Gene description

GRB2-related adaptor protein-like

Protein class

Predicted intracellular proteins

Predicted localization

Intracellular

Number of transcripts

4
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HUMAN PROTEIN ATLAS INFORMATION

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RNA tissue category

HPA:Tissue enhanced (lymph node, spleen, tonsil)
GTEx:Not detected

Protein evidence

Evidence at transcript level

Protein localization

Moderate to strong cytoplasmic and/or nuclear positivity was observed in gastrointestinal tract, hepatocytes, pancreas, adrenal gland, renal tubules, uterine glands, cells of male genital tract, Purkinje cells and myocytes. Remaining normal tissues were in general negative.

ANTIBODY RELIABILITY

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Data reliability
description

Pending RNA-based expert annotation.

Data reliability

Uncertain based on 1 antibody.
HPA051796
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RNA AND PROTEIN EXPRESSION SUMMARY

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RNA expression (FPKM) Protein expression (score)
Brain
Endocrine tissues
Bone marrow & immune system
Muscle tissues
Lung
Liver & gallbladder
Pancreas
Gastrointestinal tract
Kidney & urinary bladder
Male tissues
Female tissues
Adipose & soft tissue
Skin
Cerebral cortex

Lymph node

Liver

Colon

Kidney

Testis



PROTEIN EXPRESSION OVERVIEW

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Organ

Expression



RNA EXPRESSION OVERVIEW

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HPA dataset
RNA tissue category:  Tissue enhanced (lymph node, spleen, tonsil)

Organ

Expression

GTEx dataset
RNA tissue category:  Not detected

Organ

Expression



GENE INFORMATION

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Gene name

GRAPL

Synonyms

Description

GRB2-related adaptor protein-like (HGNC Symbol)

Entrez gene summary

Chromosome

17

Cytoband

p11.2

Chromosome location (bp)

19127469 - 19159176

Protein evidence

Evidence at transcript level (all genes)

Ensembl

ENSG00000189152 (version 78.38)

Entrez gene

400581

UniProt

Q8TC17 (UniProt - Inferred from homology)

neXtProt

NX_Q8TC17

Antibodypedia

GRAPL antibodies


PROTEIN BROWSER

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ENST00000344415
 
ENST00000437957
 
ENST00000574324
 
ENST00000577213
 
 
 
 


PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

GRAPL-001 ENSP00000437409
ENST00000344415
Q8TC17
Show all »
Show » Show » 118 13.4 No 0
GRAPL-003 ENSP00000465788
ENST00000437957
K7EKU7
Show all »
Show » Show » 70 8.2 No 0
GRAPL-004 ENSP00000459618
ENST00000574324
Show » 65 7.2 No 0
GRAPL-005 ENSP00000466091
ENST00000577213
K7ELI1
Show all »
Show » Show » 100 11.5 No 0