MMP23B

GENERAL INFORMATION

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Gene name

MMP23B

Gene description

Matrix metallopeptidase 23B

Protein class

Enzymes
FDA approved drug targets
Predicted intracellular proteins

Predicted localization

Intracellular

Number of transcripts

8
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HUMAN PROTEIN ATLAS INFORMATION

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RNA tissue category

HPA:Mixed
GTEx:Tissue enhanced (ovary)

Protein evidence

Evidence at protein level

Protein localization

Glandular epithelium in gastrointestinal tract and seminal vesicle showed strong granular cytoplasmic positivity. Remaining normal cells were negative.

ANTIBODY RELIABILITY

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Data reliability
description

Pending RNA-based expert annotation.

Data reliability

Uncertain based on 1 antibody.
CAB002768
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RNA AND PROTEIN EXPRESSION SUMMARY

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RNA expression (FPKM) Protein expression (score)
Brain
Endocrine tissues
Bone marrow & immune system
Muscle tissues
Lung
Nasopharynx
N/A
N/A
Bronchus
N/A
Liver & gallbladder
Pancreas
Gastrointestinal tract
Kidney & urinary bladder
Male tissues
Female tissues
Adipose & soft tissue
Skin
Cerebral cortex

Lymph node

Liver

Colon

Kidney

Testis



PROTEIN EXPRESSION OVERVIEW

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Organ

Expression



RNA EXPRESSION OVERVIEW

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HPA dataset
RNA tissue category:  Mixed

Organ

Expression

GTEx dataset
RNA tissue category:  Tissue enhanced (ovary)

Organ

Expression



GENE INFORMATION

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Gene name

MMP23B (HGNC Symbol)

Synonyms

MIFR, MIFR-1, MMP22

Description

Matrix metallopeptidase 23B (HGNC Symbol)

Entrez gene summary

This gene (MMP23B) encodes a member of the matrix metalloproteinase (MMP) family, and it is part of a duplicated region of chromosome 1p36.3. Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. This gene belongs to the more telomeric copy of the duplicated region. [provided by RefSeq, Jul 2008]

Chromosome

1

Cytoband

p36.33

Chromosome location (bp)

1632095 - 1701810

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000189409 (version 78.38)

Entrez gene

8510

UniProt

O75900 (UniProt - Evidence at protein level)

neXtProt

NX_O75900

Antibodypedia

MMP23B antibodies


PROTEIN BROWSER

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ENST00000356026
 
ENST00000378675
 
ENST00000412810
 
ENST00000435358
 
ENST00000472264
 
ENST00000479814
 
ENST00000503792
 
ENST00000618459
 
 
 
 


PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

MMP23B-001 ENSP00000348308
ENST00000356026
O75900
Show all »
Show » Show » 390 43.9 No 0
MMP23B-002 ENSP00000367945
ENST00000378675
O75086
Show all »
Show » Show » 386 41.6 No 0
MMP23B-003 ENSP00000426293
ENST00000479814
H0YA69
Show all »
Show » 265 28.8 No 0
MMP23B-004 ENSP00000405867
ENST00000435358
Show » Show » 242 26.5 No 0
MMP23B-005 ENSP00000424976
ENST00000472264
D6REP6
Show all »
Show » 166 17.2 No 0
MMP23B-010 ENSP00000426857
ENST00000503792
H0YAE5
Show all »
Show » 258 27.4 No 0
MMP23B-201 ENSP00000482367
ENST00000412810
O75900
Show all »
Show » Show » 390 43.9 No 0
MMP23B-202 ENSP00000482664
ENST00000618459
O75086
Show all »
Show » Show » 386 41.6 No 0